2rfx: Difference between revisions

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New page: '''Unreleased structure''' The entry 2rfx is ON HOLD until Paper Publication Authors: Chessman, D., Kostenko, L., Lethborg, T., Purcell, A.W., Williamson, N.A., Kjer-Nielsen, L., Mifsud...
 
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'''Unreleased structure'''
{{Seed}}
[[Image:2rfx.jpg|left|200px]]


The entry 2rfx is ON HOLD until Paper Publication
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Authors: Chessman, D., Kostenko, L., Lethborg, T., Purcell, A.W., Williamson, N.A., Kjer-Nielsen, L., Mifsud, N.A., Tait, B.D., Holdsworth, R., Almeida, C.A., Nolan, D., Macdonald, W.A., Archbold, J.K., Kellerher, A.D., Mallal, S., Bharadwaj, M., Rossjohn, J., McC
===Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF===


Description: Crystal Structure of HLA-B*5701, presenting the self peptide, LSSPVTKSF


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==Disease==
Known disease associated with this structure: Abacavir hypersensitivity, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142830 142830]], Spondyloarthropathy, susceptibility to, 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142830 142830]], Stevens-Johnson syndrome, carbamazepine-induced, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=142830 142830]], Hypoproteinemia, hypercatabolic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=109700 109700]]
 
==About this Structure==
2RFX is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFX OCA].
 
==Reference==
Human leukocyte antigen class I-restricted activation of CD8+ T cells provides the immunogenetic basis of a systemic drug hypersensitivity., Chessman D, Kostenko L, Lethborg T, Purcell AW, Williamson NA, Chen Z, Kjer-Nielsen L, Mifsud NA, Tait BD, Holdsworth R, Almeida CA, Nolan D, Macdonald WA, Archbold JK, Kellerher AD, Marriott D, Mallal S, Bharadwaj M, Rossjohn J, McCluskey J, Immunity. 2008 Jun;28(6):822-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18549801 18549801]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Archbold, J K.]]
[[Category: Macdonald, W A.]]
[[Category: McCluskey, J.]]
[[Category: Rossjohn, J.]]
[[Category: Alpha beta sandwich-immunologlobulin like]]
[[Category: Disease mutation]]
[[Category: Glycation]]
[[Category: Glycoprotein]]
[[Category: Host-virus interaction]]
[[Category: Immune response]]
[[Category: Immune system]]
[[Category: Immunoglobulin domain]]
[[Category: Membrane]]
[[Category: Mhc i]]
[[Category: Polymorphism]]
[[Category: Pyrrolidone carboxylic acid]]
[[Category: Secreted]]
[[Category: Transmembrane]]
[[Category: Ubl conjugation]]
 
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