3cwe: Difference between revisions

@@ Line 1: / Line 1: @@
-[[Image:3cwe.jpg|left|200px]]
+{{Seed}}
+[[Image:3cwe.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_3cwe|  PDB=3cwe  |  SCENE=  }}
-'''PTP1B in complex with a phosphonic acid inhibitor'''
+===PTP1B in complex with a phosphonic acid inhibitor===
-==Overview==
+<!--
-A series of quinoline/naphthalene-difluoromethylphosphonates were prepared and were found to be potent PTP1B inhibitors. Most of these compounds bearing polar functionalities or large lipophilic residues did not show appreciable oral bioavailability in rodents while small and less polar analogs displayed moderate to good oral bioavailability. The title compound was found to have the best overall potency and pharmacokinetic profile and was found to be efficacious in animal models of diabetes and cancer.
+The line below this paragraph, {{ABSTRACT_PUBMED_18477508}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18477508 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18477508}}
 ==About this Structure==
@@ Line 38: / Line 42: @@
 [[Category: Polymorphism]]
 [[Category: Protein phosphatase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 11 10:50:46 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 11:28:10 2008''

Navigation menu