3d0b: Difference between revisions

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-[[Image:3d0b.jpg|left|200px]]
+{{Seed}}
+[[Image:3d0b.png|left|200px]]
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 {{STRUCTURE_3d0b|  PDB=3d0b  |  SCENE=  }}
-'''Crystal Structure of Benzamide Tetrahydro-4H-carbazol-4-one bound to Hsp90'''
+===Crystal Structure of Benzamide Tetrahydro-4H-carbazol-4-one bound to Hsp90===
-==Overview==
+<!--
-Hsp90 maintains the conformational stability of multiple proteins implicated in oncogenesis and has emerged as a target for chemotherapy. We report here the discovery of a novel small molecule scaffold that inhibits Hsp90. X-ray data show that the scaffold binds competitively at the ATP site on Hsp90. Cellular proliferation and client assays demonstrate that members of the series are able to inhibit Hsp90 at nanomolar concentrations.
+The line below this paragraph, {{ABSTRACT_PUBMED_18511277}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18511277 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18511277}}
 ==About this Structure==
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 [[Category: Phosphoprotein]]
 [[Category: Stress response]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 18 12:12:17 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 07:47:40 2008''

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