Biological Unit: Difference between revisions
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Eric Martz (talk | contribs) →Probable Quaternary Structure Server (PQS): polishing |
Eric Martz (talk | contribs) →Probable Quaternary Structure Server (PQS): polishing |
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The [http://pqs.ebi.ac.uk Probable Quaternary Structure Server] (PQS) at the European Bioinformatics Institute examines the inter-chain contacts within protein crystals, and makes an educated guess (using published methods) about which contacts represent co-evolved specific oligomeric contacts, and which are artifacts of crystallization. It is usually correct, but not always. It returns models for what it deduces to be the biological units. There are many possible relationships between the asymmetric unit and the biological units returned by PQS. Examples are given in the discussion of [http://proteinexplorer.org/pqs.htm PQS at ProteinExplorer.Org]. | The [http://pqs.ebi.ac.uk Probable Quaternary Structure Server] (PQS) at the European Bioinformatics Institute examines the inter-chain contacts within protein crystals, and makes an educated guess (using published methods) about which contacts represent co-evolved specific oligomeric contacts, and which are artifacts of crystallization. It is usually correct, but not always. It returns models for what it deduces to be the biological units. There are many possible relationships between the asymmetric unit and the biological units returned by PQS. Examples are given in the discussion of [http://proteinexplorer.org/pqs.htm PQS at ProteinExplorer.Org]. | ||
==Web Sites== | ==Web Sites== | ||