Collagen: Difference between revisions

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This illustration depicts a basement membrane, which forms a tough surface that supports the skin and many organs. A different collagen--"type IV"--forms the structural basis of this membrane. Type IV collagen has a globular head at one end and an extra tail at the other. The heads bind strongly together, head-to-head, and four collagen molecules associate together through their tails, forming an X-shaped complex. Using these two types of interactions, type IV collagen forms an extended network, shown above in light blue. Two other molecules--cross-shaped laminin (blue- green) and long, snaky proteoglycans (green)--fill in the spaces, forming a dense sheet.
This illustration depicts a basement membrane, which forms a tough surface that supports the skin and many organs. A different collagen--"type IV"--forms the structural basis of this membrane. Type IV collagen has a globular head at one end and an extra tail at the other. The heads bind strongly together, head-to-head, and four collagen molecules associate together through their tails, forming an X-shaped complex. Using these two types of interactions, type IV collagen forms an extended network, shown above in light blue. Two other molecules--cross-shaped laminin (blue- green) and long, snaky proteoglycans (green)--fill in the spaces, forming a dense sheet.
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== Content Donators ==
Currently (June 22 2008), most all of the textual and image content of this page is the work of David S. Goodsell, who has given permission for its inclusion in [[Proteopedia]]:
* Content adapted with permission from David S. Goodsell's [http://mgl.scripps.edu/people/goodsell/pdb/pdb4/pdb4_1.html Molecule of the Month on Collagen]




==Another Jmol tutorial==
==Another Jmol tutorial==
[http://www.messiah.edu/molscilab/Jmol/collagen/collagen_index.htm Tutorial] which illustrates and describes the 3D structure of collagen
[http://www.messiah.edu/molscilab/Jmol/collagen/collagen_index.htm Tutorial] which illustrates and describes the 3D structure of collagen
* Content adapted with permission from David S. Goodsell's [http://mgl.scripps.edu/people/goodsell/pdb/pdb4/pdb4_1.html Molecule of the Month on Collagen]