1dpw: Difference between revisions
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New page: left|200px<br /><applet load="1dpw" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dpw, resolution 1.64Å" /> '''STRUCTURE OF HEN EGG... |
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[[Image:1dpw.jpg|left|200px]]<br /><applet load="1dpw" size=" | [[Image:1dpw.jpg|left|200px]]<br /><applet load="1dpw" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1dpw, resolution 1.64Å" /> | caption="1dpw, resolution 1.64Å" /> | ||
'''STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH MPD'''<br /> | '''STRUCTURE OF HEN EGG-WHITE LYSOZYME IN COMPLEX WITH MPD'''<br /> | ||
==Overview== | ==Overview== | ||
Hen egg-white lysozyme has been crystallized at slightly alkaline pH using | Hen egg-white lysozyme has been crystallized at slightly alkaline pH using 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly isomorphous to crystals grown at acidic pH using sodium chloride as the precipitant. However, the growth kinetics differ markedly between the two conditions. The major reason for this is a molecule of MPD that binds tightly in between two lysozyme molecules and favors the growth of the crystals along the crystallographic c direction over growth perpendicular to it. | ||
==About this Structure== | ==About this Structure== | ||
1DPW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with CL, TRS and MRD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http:// | 1DPW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=TRS:'>TRS</scene> and <scene name='pdbligand=MRD:'>MRD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DPW OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Hilgenfeld, R.]] | [[Category: Hilgenfeld, R.]] | ||
[[Category: Palm, G | [[Category: Palm, G J.]] | ||
[[Category: Weiss, M | [[Category: Weiss, M S.]] | ||
[[Category: CL]] | [[Category: CL]] | ||
[[Category: MRD]] | [[Category: MRD]] | ||
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[[Category: protein-mpd complex]] | [[Category: protein-mpd complex]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:19:10 2008'' | ||
