1dus: Difference between revisions

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[[Image:1dus.gif|left|200px]]<br /><applet load="1dus" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1dus.gif|left|200px]]<br /><applet load="1dus" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1dus, resolution 1.80Å" />

'''MJ0882-A hypothetical protein from M. jannaschii'''<br />

==Overview==

We have determined the three-dimensional (3-D) structure of protein, MJ0882, which derives from a hypothetical open reading frame in the genome, of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882, at 1.8 A highly resembles that of a methyltransferase, despite limited, sequence similarity to any confirmed methyltransferase. The structure has, an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with, similarities to those commonly found among AdoMet binding proteins., Preliminary biochemical experiments show that MJ0882 specifically binds to, AdoMet, which is the essential co-factor for methyltransferases.

We have determined the three-dimensional (3-D) structure of protein MJ0882, which derives from a hypothetical open reading frame in the genome of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882 at 1.8 A highly resembles that of a methyltransferase, despite limited sequence similarity to any confirmed methyltransferase. The structure has an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with similarities to those commonly found among AdoMet binding proteins. Preliminary biochemical experiments show that MJ0882 specifically binds to AdoMet, which is the essential co-factor for methyltransferases.

==About this Structure==

1DUS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1DUS OCA].

1DUS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUS OCA].

==Reference==

Line 13:

[[Category: Methanocaldococcus jannaschii]]

[[Category: Single protein]]

[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]

[[Category: BSGC, Berkeley Structural Genomics Center.]]

[[Category: Huang, L.]]

[[Category: Hung, L.]]

[[Category: Kim, R.]]

[[Category: Kim, S.H.]]

[[Category: Kim, S H.]]

[[Category: berkeley structural genomics center]]

[[Category: bsgc structure funded by nih]]

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[[Category: structural genomics]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:20:40 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1dus.gif|left|200px]]<br /><applet load="1dus" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1dus.gif|left|200px]]<br /><applet load="1dus" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1dus, resolution 1.80&Aring;" />
 '''MJ0882-A hypothetical protein from M. jannaschii'''<br />
 ==Overview==
-We have determined the three-dimensional (3-D) structure of protein, MJ0882, which derives from a hypothetical open reading frame in the genome, of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882, at 1.8 A highly resembles that of a methyltransferase, despite limited, sequence similarity to any confirmed methyltransferase. The structure has, an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with, similarities to those commonly found among AdoMet binding proteins., Preliminary biochemical experiments show that MJ0882 specifically binds to, AdoMet, which is the essential co-factor for methyltransferases.
+We have determined the three-dimensional (3-D) structure of protein MJ0882, which derives from a hypothetical open reading frame in the genome of the hyperthermophile Methanococcus jannaschii. The 3-D fold of MJ0882 at 1.8 A highly resembles that of a methyltransferase, despite limited sequence similarity to any confirmed methyltransferase. The structure has an S-adenosylmethionine (AdoMet) binding pocket surrounded by motifs with similarities to those commonly found among AdoMet binding proteins. Preliminary biochemical experiments show that MJ0882 specifically binds to AdoMet, which is the essential co-factor for methyltransferases.
 ==About this Structure==
-DUS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DUS OCA].
+DUS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DUS OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Methanocaldococcus jannaschii]]
 [[Category: Single protein]]
-[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
+[[Category: BSGC, Berkeley Structural Genomics Center.]]
 [[Category: Huang, L.]]
 [[Category: Hung, L.]]
 [[Category: Kim, R.]]
-[[Category: Kim, S.H.]]
+[[Category: Kim, S H.]]
 [[Category: berkeley structural genomics center]]
 [[Category: bsgc structure funded by nih]]
@@ Line 26: / Line 26: @@
 [[Category: structural genomics]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 13:36:07 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:20:40 2008''