1ecr: Difference between revisions

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New page: left|200px<br /><applet load="1ecr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ecr, resolution 2.700Å" /> '''ESCHERICHIA COLI RE...
 
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[[Image:1ecr.gif|left|200px]]<br /><applet load="1ecr" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:1ecr.gif|left|200px]]<br /><applet load="1ecr" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="1ecr, resolution 2.700&Aring;" />
caption="1ecr, resolution 2.700&Aring;" />
'''ESCHERICHIA COLI REPLICATION TERMINATOR PROTEIN (TUS) COMPLEXED WITH DNA'''<br />
'''ESCHERICHIA COLI REPLICATION TERMINATOR PROTEIN (TUS) COMPLEXED WITH DNA'''<br />


==Overview==
==Overview==
The crystal structure of the Escherichia coli replication-terminator, protein (Tus) bound to terminus-site (Ter) DNA has been determined at 2.7, A resolution. The Tus protein folds into a previously undescribed, architecture divided into two domains by a central basic cleft. This cleft, accommodates locally deformed B-form Ter DNA and makes extensive contacts, with the major groove, mainly through two interdomain beta-strands. The, unusual structural features of this complex may explain how the, replication fork is halted in only one direction.
The crystal structure of the Escherichia coli replication-terminator protein (Tus) bound to terminus-site (Ter) DNA has been determined at 2.7 A resolution. The Tus protein folds into a previously undescribed architecture divided into two domains by a central basic cleft. This cleft accommodates locally deformed B-form Ter DNA and makes extensive contacts with the major groove, mainly through two interdomain beta-strands. The unusual structural features of this complex may explain how the replication fork is halted in only one direction.


==About this Structure==
==About this Structure==
1ECR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ECR OCA].  
1ECR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ECR OCA].  


==Reference==
==Reference==
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[[Category: dna-binding]]
[[Category: dna-binding]]


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