1ecr: Difference between revisions
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New page: left|200px<br /><applet load="1ecr" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ecr, resolution 2.700Å" /> '''ESCHERICHIA COLI RE... |
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[[Image:1ecr.gif|left|200px]]<br /><applet load="1ecr" size=" | [[Image:1ecr.gif|left|200px]]<br /><applet load="1ecr" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1ecr, resolution 2.700Å" /> | caption="1ecr, resolution 2.700Å" /> | ||
'''ESCHERICHIA COLI REPLICATION TERMINATOR PROTEIN (TUS) COMPLEXED WITH DNA'''<br /> | '''ESCHERICHIA COLI REPLICATION TERMINATOR PROTEIN (TUS) COMPLEXED WITH DNA'''<br /> | ||
==Overview== | ==Overview== | ||
The crystal structure of the Escherichia coli replication-terminator | The crystal structure of the Escherichia coli replication-terminator protein (Tus) bound to terminus-site (Ter) DNA has been determined at 2.7 A resolution. The Tus protein folds into a previously undescribed architecture divided into two domains by a central basic cleft. This cleft accommodates locally deformed B-form Ter DNA and makes extensive contacts with the major groove, mainly through two interdomain beta-strands. The unusual structural features of this complex may explain how the replication fork is halted in only one direction. | ||
==About this Structure== | ==About this Structure== | ||
1ECR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http:// | 1ECR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ECR OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: dna-binding]] | [[Category: dna-binding]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:26:21 2008'' | ||