1ej6: Difference between revisions

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New page: left|200px<br /><applet load="1ej6" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ej6, resolution 3.6Å" /> '''Reovirus core'''<br /...
 
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[[Image:1ej6.gif|left|200px]]<br /><applet load="1ej6" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:1ej6.gif|left|200px]]<br /><applet load="1ej6" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="1ej6, resolution 3.6&Aring;" />
caption="1ej6, resolution 3.6&Aring;" />
'''Reovirus core'''<br />
'''Reovirus core'''<br />


==Overview==
==Overview==
The reovirus core is an assembly with a relative molecular mass of 52, million that synthesizes, modifies and exports viral messenger RNA., Analysis of its structure by X-ray crystallography shows that there are, alternative, specific and completely non-equivalent contacts made by, several surfaces of two of its proteins; that the RNA capping and export, apparatus is a hollow cylinder, which probably sequesters its substrate to, ensure completion of the capping reactions; that the genomic, double-stranded RNA is coiled into concentric layers within the particle;, and that there is a protein shell that appears to be common to all groups, of double-stranded RNA viruses.
The reovirus core is an assembly with a relative molecular mass of 52 million that synthesizes, modifies and exports viral messenger RNA. Analysis of its structure by X-ray crystallography shows that there are alternative, specific and completely non-equivalent contacts made by several surfaces of two of its proteins; that the RNA capping and export apparatus is a hollow cylinder, which probably sequesters its substrate to ensure completion of the capping reactions; that the genomic double-stranded RNA is coiled into concentric layers within the particle; and that there is a protein shell that appears to be common to all groups of double-stranded RNA viruses.


==About this Structure==
==About this Structure==
1EJ6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1EJ6 OCA].  
1EJ6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Reovirus_sp. Reovirus sp.] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EJ6 OCA].  


==Reference==
==Reference==
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[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Reovirus sp.]]
[[Category: Reovirus sp.]]
[[Category: Harrison, S.C.]]
[[Category: Harrison, S C.]]
[[Category: Nibert, M.L.]]
[[Category: Nibert, M L.]]
[[Category: Reinisch, K.M.]]
[[Category: Reinisch, K M.]]
[[Category: ZN]]
[[Category: ZN]]
[[Category: dsrna virus]]
[[Category: dsrna virus]]
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[[Category: zinc finger]]
[[Category: zinc finger]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 14:02:44 2007''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:28:19 2008''