1elo: Difference between revisions

Line 1:

[[Image:1elo.gif|left|200px]]<br /><applet load="1elo" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1elo.gif|left|200px]]<br /><applet load="1elo" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1elo, resolution 2.8Å" />

'''ELONGATION FACTOR G WITHOUT NUCLEOTIDE'''<br />

==Overview==

The crystal structure of Thermus thermophilus elongation factor G without, guanine nucleotide was determined to 2.85 A. This GTPase has five domains, with overall dimensions of 50 x 60 x 118 A. The GTP binding domain has a, core common to other GTPases with a unique subdomain which probably, functions as an intrinsic nucleotide exchange factor. Domains I and II are, homologous to elongation factor Tu and their arrangement, both with and, without GDP, is more similar to elongation factor Tu in complex with a GTP, analogue than with GDP. Domains III and V show structural similarities to, ribosomal proteins. Domain IV protrudes from the main body of the protein, and has an extraordinary topology with a left-handed cross-over connection, between two parallel beta-strands.

The crystal structure of Thermus thermophilus elongation factor G without guanine nucleotide was determined to 2.85 A. This GTPase has five domains with overall dimensions of 50 x 60 x 118 A. The GTP binding domain has a core common to other GTPases with a unique subdomain which probably functions as an intrinsic nucleotide exchange factor. Domains I and II are homologous to elongation factor Tu and their arrangement, both with and without GDP, is more similar to elongation factor Tu in complex with a GTP analogue than with GDP. Domains III and V show structural similarities to ribosomal proteins. Domain IV protrudes from the main body of the protein and has an extraordinary topology with a left-handed cross-over connection between two parallel beta-strands.

==About this Structure==

1ELO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1ELO OCA].

1ELO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELO OCA].

==Reference==

Line 19:

[[Category: Garber, M.]]

[[Category: Liljas, A.]]

[[Category: Svensson, L.A.]]

[[Category: Svensson, L A.]]

[[Category: Zheltonosova, J.]]

[[Category: elongation factor]]

Line 26:

[[Category: ribosomal translocase]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20 14~~:06:~~47 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:29:03 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1elo.gif|left|200px]]<br /><applet load="1elo" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1elo.gif|left|200px]]<br /><applet load="1elo" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1elo, resolution 2.8&Aring;" />
 '''ELONGATION FACTOR G WITHOUT NUCLEOTIDE'''<br />
 ==Overview==
-The crystal structure of Thermus thermophilus elongation factor G without, guanine nucleotide was determined to 2.85 A. This GTPase has five domains, with overall dimensions of 50 x 60 x 118 A. The GTP binding domain has a, core common to other GTPases with a unique subdomain which probably, functions as an intrinsic nucleotide exchange factor. Domains I and II are, homologous to elongation factor Tu and their arrangement, both with and, without GDP, is more similar to elongation factor Tu in complex with a GTP, analogue than with GDP. Domains III and V show structural similarities to, ribosomal proteins. Domain IV protrudes from the main body of the protein, and has an extraordinary topology with a left-handed cross-over connection, between two parallel beta-strands.
+The crystal structure of Thermus thermophilus elongation factor G without guanine nucleotide was determined to 2.85 A. This GTPase has five domains with overall dimensions of 50 x 60 x 118 A. The GTP binding domain has a core common to other GTPases with a unique subdomain which probably functions as an intrinsic nucleotide exchange factor. Domains I and II are homologous to elongation factor Tu and their arrangement, both with and without GDP, is more similar to elongation factor Tu in complex with a GTP analogue than with GDP. Domains III and V show structural similarities to ribosomal proteins. Domain IV protrudes from the main body of the protein and has an extraordinary topology with a left-handed cross-over connection between two parallel beta-strands.
 ==About this Structure==
-ELO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ELO OCA].
+ELO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ELO OCA].
 ==Reference==
@@ Line 19: / Line 19: @@
 [[Category: Garber, M.]]
 [[Category: Liljas, A.]]
-[[Category: Svensson, L.A.]]
+[[Category: Svensson, L A.]]
 [[Category: Zheltonosova, J.]]
 [[Category: elongation factor]]
@@ Line 26: / Line 26: @@
 [[Category: ribosomal translocase]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 14:06:47 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:29:03 2008''