1gd6: Difference between revisions

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[[Image:1gd6.gif|left|200px]]<br /><applet load="1gd6" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1gd6.gif|left|200px]]<br /><applet load="1gd6" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1gd6, resolution 2.5Å" />

'''STRUCTURE OF THE BOMBYX MORI LYSOZYME'''<br />

==Overview==

Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme., BmLZ has considerable activity at low temperatures and low activation, energies compared with those of hen egg white lysozyme (HEWLZ), according, to measurements of the temperature dependencies of relative activity, (lytic and glycol chitin) and the estimation of activation energies using, the Arrhenius equation. Being so active at low temperatures and low, activation energies is characteristic of psychrophilic (cold-adapted), enzymes. The three-dimensional structure of BmLZ has been determined by, X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is, similar to that of c-type lysozymes. However, BmLZ shows some distinct, differences in the two exposed loops and the C-terminal region. A detailed, comparison of BmLZ and HEWLZ suggests structural rationalizations for the, differences in the catalytic efficiency, stability, and mode of activity, between these two lysozymes.

Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme. BmLZ has considerable activity at low temperatures and low activation energies compared with those of hen egg white lysozyme (HEWLZ), according to measurements of the temperature dependencies of relative activity (lytic and glycol chitin) and the estimation of activation energies using the Arrhenius equation. Being so active at low temperatures and low activation energies is characteristic of psychrophilic (cold-adapted) enzymes. The three-dimensional structure of BmLZ has been determined by X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is similar to that of c-type lysozymes. However, BmLZ shows some distinct differences in the two exposed loops and the C-terminal region. A detailed comparison of BmLZ and HEWLZ suggests structural rationalizations for the differences in the catalytic efficiency, stability, and mode of activity between these two lysozymes.

==About this Structure==

1GD6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1GD6 OCA].

1GD6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GD6 OCA].

==Reference==

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[[Category: lysozyme]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:48:49 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1gd6.gif|left|200px]]<br /><applet load="1gd6" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1gd6.gif|left|200px]]<br /><applet load="1gd6" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1gd6, resolution 2.5&Aring;" />
 '''STRUCTURE OF THE BOMBYX MORI LYSOZYME'''<br />
 ==Overview==
-Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme., BmLZ has considerable activity at low temperatures and low activation, energies compared with those of hen egg white lysozyme (HEWLZ), according, to measurements of the temperature dependencies of relative activity, (lytic and glycol chitin) and the estimation of activation energies using, the Arrhenius equation. Being so active at low temperatures and low, activation energies is characteristic of psychrophilic (cold-adapted), enzymes. The three-dimensional structure of BmLZ has been determined by, X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is, similar to that of c-type lysozymes. However, BmLZ shows some distinct, differences in the two exposed loops and the C-terminal region. A detailed, comparison of BmLZ and HEWLZ suggests structural rationalizations for the, differences in the catalytic efficiency, stability, and mode of activity, between these two lysozymes.
+Bombyx mori lysozyme (BmLZ), from the silkworm, is an insect lysozyme. BmLZ has considerable activity at low temperatures and low activation energies compared with those of hen egg white lysozyme (HEWLZ), according to measurements of the temperature dependencies of relative activity (lytic and glycol chitin) and the estimation of activation energies using the Arrhenius equation. Being so active at low temperatures and low activation energies is characteristic of psychrophilic (cold-adapted) enzymes. The three-dimensional structure of BmLZ has been determined by X-ray crystallography at 2.5 A resolution. The core structure of BmLZ is similar to that of c-type lysozymes. However, BmLZ shows some distinct differences in the two exposed loops and the C-terminal region. A detailed comparison of BmLZ and HEWLZ suggests structural rationalizations for the differences in the catalytic efficiency, stability, and mode of activity between these two lysozymes.
 ==About this Structure==
-GD6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1GD6 OCA].
+GD6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GD6 OCA].
 ==Reference==
@@ Line 25: / Line 25: @@
 [[Category: lysozyme]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 15:57:32 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 12:48:49 2008''