3d14: Difference between revisions

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~~'''Unreleased structure'''~~

[[Image:3d14.jpg|left|200px]]

The ~~entry~~ 3d14 ~~is ON HOLD~~ ~~until Paper Publication~~

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~~Authors: Elling, R.~~A~~., Baskaran, S., Allen, D.A., Oslob~~, ~~J.D.~~, ~~Romanowski~~, ~~M.J.~~

===Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea===

Description: Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]-thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri Jul~~ 11 13:04:40 2008''

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==About this Structure==

3D14 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D14 OCA].

==Reference==

Discovery of a potent and selective Aurora kinase inhibitor., Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, McDowell RS, Nannini MA, Shen W, Silverman JA, Sopko MM, Tangonan BT, Teague J, Yoburn JC, Yu CH, Zhong M, Zimmerman KM, O'Brien T, Lew W, Bioorg Med Chem Lett. 2008 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18678489 18678489]

[[Category: Mus musculus]]

[[Category: Non-specific serine/threonine protein kinase]]

[[Category: Single protein]]

[[Category: Allen, D A.]]

[[Category: Baskaran, S.]]

[[Category: Elling, R A.]]

[[Category: Oslob, J D.]]

[[Category: Romanowski, M J.]]

[[Category: Aurora some]]

[[Category: Kinase]]

[[Category: Small-molecule inhibitor]]

[[Category: Transferase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:27:17 2008''

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
+[[Image:3d14.jpg|left|200px]]
-The entry 3d14 is ON HOLD  until Paper Publication
+<!--
+The line below this paragraph, containing "STRUCTURE_3d14", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3d14|  PDB=3d14  |  SCENE=  }}
-Authors: Elling, R.A., Baskaran, S., Allen, D.A., Oslob, J.D., Romanowski, M.J.
+===Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]- thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea===
-Description: Crystal structure of mouse Aurora A (Asn186->Gly, Lys240->Arg, Met302->Leu) in complex with 1-{5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)-ethyl]-thiazol-2-yl}-3-(3-trifluoromethyl-phenyl)-urea
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jul 11 13:04:40 2008''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18678489}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18678489 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18678489}}
+==About this Structure==
+D14 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3D14 OCA].
+==Reference==
+Discovery of a potent and selective Aurora kinase inhibitor., Oslob JD, Romanowski MJ, Allen DA, Baskaran S, Bui M, Elling RA, Flanagan WM, Fung AD, Hanan EJ, Harris S, Heumann SA, Hoch U, Jacobs JW, Lam J, Lawrence CE, McDowell RS, Nannini MA, Shen W, Silverman JA, Sopko MM, Tangonan BT, Teague J, Yoburn JC, Yu CH, Zhong M, Zimmerman KM, O'Brien T, Lew W, Bioorg Med Chem Lett. 2008 Jul 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18678489 18678489]
+[[Category: Mus musculus]]
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Single protein]]
+[[Category: Allen, D A.]]
+[[Category: Baskaran, S.]]
+[[Category: Elling, R A.]]
+[[Category: Oslob, J D.]]
+[[Category: Romanowski, M J.]]
+[[Category: Aurora some]]
+[[Category: Kinase]]
+[[Category: Small-molecule inhibitor]]
+[[Category: Transferase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:27:17 2008''