3dg8: Difference between revisions
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New page: '''Unreleased structure''' The entry 3dg8 is ON HOLD until Paper Publication Authors: Dasgupta, T., Chitnumsub, P., Maneeruttanarungroj, C., Kamchonwongpaisan, S., Nichols, S., Lyons, T... |
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===Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP=== | |||
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{{ABSTRACT_PUBMED_19146480}} | |||
==About this Structure== | |||
3DG8 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DG8 OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:19146480</ref><references group="xtra"/> | |||
[[Category: Plasmodium falciparum]] | |||
[[Category: Anderson, K S.]] | |||
[[Category: Chitnumsub, P.]] | |||
[[Category: Dasgupta, T.]] | |||
[[Category: Jorgensen, W L.]] | |||
[[Category: Kamchonwongpaisan, S.]] | |||
[[Category: Lyons, T M.]] | |||
[[Category: Maneeruttanarungroj, C.]] | |||
[[Category: Nichols, S.]] | |||
[[Category: Tirado-Rives, J.]] | |||
[[Category: Yuthavong, Y.]] | |||
[[Category: Alpha-beta]] | |||
[[Category: Methyltransferase]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Transferase]] | |||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jan 28 09:48:23 2009'' | |||
Revision as of 07:48, 28 January 2009
Quadruple mutant (N51I+C59R+S108N+I164L) Plasmodium falciparum dihydrofolate reductase-thymidylate synthase (PfDHFR-TS) complexed with RJF670, NADPH, and dUMP
Template:ABSTRACT PUBMED 19146480
About this Structure
3DG8 is a 4 chains structure of sequences from Plasmodium falciparum. Full crystallographic information is available from OCA.
Reference
- Dasgupta T, Chitnumsub P, Kamchonwongpaisan S, Maneeruttanarungroj C, Nichols SE, Lyons TM, Tirado-Rives J, Jorgensen WL, Yuthavong Y, Anderson KS. Exploiting structural analysis, in silico screening, and serendipity to identify novel inhibitors of drug-resistant falciparum malaria. ACS Chem Biol. 2009 Jan 16;4(1):29-40. PMID:19146480 doi:10.1021/cb8002804
Page seeded by OCA on Wed Jan 28 09:48:23 2009
