1jgo: Difference between revisions

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[[Image:1jgo.gif|left|200px]]<br /><applet load="1jgo" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1jgo.gif|left|200px]]<br /><applet load="1jgo" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1jgo, resolution 5.6Å" />

'''The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY'''<br />

==Overview==

Using X-ray crystallography, we have directly observed the path of mRNA in, the 70S ribosome in Fourier difference maps at 7 A resolution. About 30, nucleotides of the mRNA are wrapped in a groove that encircles the neck of, the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft, between the head and the back of the platform. At the interface, only, about eight nucleotides (-1 to +7), centered on the junction between the A, and P codons, are exposed, and bond almost exclusively to 16S rRNA. The, mRNA enters the ribosome around position +13 to +15, the location of, downstream pseudoknots that stimulate -1 translational frame shifting.

Using X-ray crystallography, we have directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 A resolution. About 30 nucleotides of the mRNA are wrapped in a groove that encircles the neck of the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft between the head and the back of the platform. At the interface, only about eight nucleotides (-1 to +7), centered on the junction between the A and P codons, are exposed, and bond almost exclusively to 16S rRNA. The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting.

==About this Structure==

1JGO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1JGO OCA].

1JGO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGO OCA].

==Reference==

Line 13:

[[Category: Protein complex]]

[[Category: Thermus thermophilus]]

[[Category: Cate, J.H.D.]]

[[Category: Cate, J H.D.]]

[[Category: Noller, H.F.]]

[[Category: Noller, H F.]]

[[Category: Yusupov, M.M.]]

[[Category: Yusupov, M M.]]

[[Category: Yusupova, G.Z.]]

[[Category: Yusupova, G Z.]]

[[Category: life]]

[[Category: protein synthesis]]

[[Category: ribosome assembly]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20 18~~:13:~~47 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:22:26 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1jgo.gif|left|200px]]<br /><applet load="1jgo" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1jgo.gif|left|200px]]<br /><applet load="1jgo" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1jgo, resolution 5.6&Aring;" />
 '''The Path of Messenger RNA Through the Ribosome. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY'''<br />
 ==Overview==
-Using X-ray crystallography, we have directly observed the path of mRNA in, the 70S ribosome in Fourier difference maps at 7 A resolution. About 30, nucleotides of the mRNA are wrapped in a groove that encircles the neck of, the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft, between the head and the back of the platform. At the interface, only, about eight nucleotides (-1 to +7), centered on the junction between the A, and P codons, are exposed, and bond almost exclusively to 16S rRNA. The, mRNA enters the ribosome around position +13 to +15, the location of, downstream pseudoknots that stimulate -1 translational frame shifting.
+Using X-ray crystallography, we have directly observed the path of mRNA in the 70S ribosome in Fourier difference maps at 7 A resolution. About 30 nucleotides of the mRNA are wrapped in a groove that encircles the neck of the 30S subunit. The Shine-Dalgarno helix is bound in a large cleft between the head and the back of the platform. At the interface, only about eight nucleotides (-1 to +7), centered on the junction between the A and P codons, are exposed, and bond almost exclusively to 16S rRNA. The mRNA enters the ribosome around position +13 to +15, the location of downstream pseudoknots that stimulate -1 translational frame shifting.
 ==About this Structure==
-JGO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1JGO OCA].
+JGO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGO OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Protein complex]]
 [[Category: Thermus thermophilus]]
-[[Category: Cate, J.H.D.]]
+[[Category: Cate, J H.D.]]
-[[Category: Noller, H.F.]]
+[[Category: Noller, H F.]]
-[[Category: Yusupov, M.M.]]
+[[Category: Yusupov, M M.]]
-[[Category: Yusupova, G.Z.]]
+[[Category: Yusupova, G Z.]]
 [[Category: life]]
 [[Category: protein synthesis]]
 [[Category: ribosome assembly]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 18:13:47 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:22:26 2008''