2hd1: Difference between revisions

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==About this Structure==
==About this Structure==
2HD1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tbm 1tbm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD1 OCA].  
2HD1 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1tbm 1tbm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HD1 OCA].  


==Reference==
==Reference==
Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding., Huai Q, Wang H, Zhang W, Colman RW, Robinson H, Ke H, Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9624-9. Epub 2004 Jun 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15210993 15210993]
<ref group="xtra">PMID:15210993</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Colman, R W.]]
[[Category: Colman, R W.]]
[[Category: Huai, Q.]]
[[Category: Huai, Q.]]
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[[Category: Pde9]]
[[Category: Pde9]]


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Revision as of 08:28, 16 February 2009

File:2hd1.png

Template:STRUCTURE 2hd1

Crystal structure of PDE9 in complex with IBMX

Template:ABSTRACT PUBMED 15210993

Disease

Known disease associated with this structure: Epilepsy, pyridoxine-dependent OMIM:[107323]

About this Structure

2HD1 is a 2 chains structure of sequences from Homo sapiens. This structure supersedes the now removed PDB entry 1tbm. Full crystallographic information is available from OCA.

Reference

  1. Huai Q, Wang H, Zhang W, Colman RW, Robinson H, Ke H. Crystal structure of phosphodiesterase 9 shows orientation variation of inhibitor 3-isobutyl-1-methylxanthine binding. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9624-9. Epub 2004 Jun 21. PMID:15210993 doi:10.1073/pnas.0401120101

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