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| ==About this Structure== | | ==About this Structure== |
| 2HAL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_a_virus Hepatitis a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAL OCA]. | | 2HAL is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hepatitis_a_virus Hepatitis a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HAL OCA]. |
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| ==Reference== | | ==Reference== |
| An episulfide cation (thiiranium ring) trapped in the active site of HAV 3C proteinase inactivated by peptide-based ketone inhibitors., Yin J, Cherney MM, Bergmann EM, Zhang J, Huitema C, Pettersson H, Eltis LD, Vederas JC, James MN, J Mol Biol. 2006 Aug 25;361(4):673-86. Epub 2006 Jul 7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16860823 16860823]
| | <ref group="xtra">PMID:16860823</ref><ref group="xtra">PMID:16288920</ref><ref group="xtra">PMID:10603326</ref><ref group="xtra">PMID:9032381</ref><references group="xtra"/> |
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| Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site., Yin J, Bergmann EM, Cherney MM, Lall MS, Jain RP, Vederas JC, James MN, J Mol Biol. 2005 Dec 9;354(4):854-71. Epub 2005 Oct 14. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16288920 16288920]
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| Crystal structure of an inhibitor complex of the 3C proteinase from hepatitis A virus (HAV) and implications for the polyprotein processing in HAV., Bergmann EM, Cherney MM, Mckendrick J, Frormann S, Luo C, Malcolm BA, Vederas JC, James MN, Virology. 1999 Dec 5;265(1):153-63. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10603326 10603326]
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| The refined crystal structure of the 3C gene product from hepatitis A virus: specific proteinase activity and RNA recognition., Bergmann EM, Mosimann SC, Chernaia MM, Malcolm BA, James MN, J Virol. 1997 Mar;71(3):2436-48. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9032381 9032381]
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| [[Category: Hepatitis a virus]] | | [[Category: Hepatitis a virus]] |
| [[Category: Picornain 3C]] | | [[Category: Picornain 3C]] |
| [[Category: Single protein]]
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| [[Category: Bergmann, E M.]] | | [[Category: Bergmann, E M.]] |
| [[Category: Cherney, M M.]] | | [[Category: Cherney, M M.]] |
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| [[Category: Picornain]] | | [[Category: Picornain]] |
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Jul 27 14:53:24 2008'' | | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 12:37:37 2009'' |
