2rfs: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
2RFS is a | 2RFS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RFS OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:18055465</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Bellon, S F.]] | [[Category: Bellon, S F.]] | ||
[[Category: Dussault, I.]] | [[Category: Dussault, I.]] | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 13:34:56 2009'' | ||
Revision as of 11:34, 16 February 2009
X-ray structure of SU11274 bound to c-Met
Template:ABSTRACT PUBMED 18055465
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
2RFS is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bellon SF, Kaplan-Lefko P, Yang Y, Zhang Y, Moriguchi J, Rex K, Johnson CW, Rose PE, Long AM, O'Connor AB, Gu Y, Coxon A, Kim TS, Tasker A, Burgess TL, Dussault I. c-Met inhibitors with novel binding mode show activity against several hereditary papillary renal cell carcinoma-related mutations. J Biol Chem. 2008 Feb 1;283(5):2675-83. Epub 2007 Nov 30. PMID:18055465 doi:10.1074/jbc.M705774200
Page seeded by OCA on Mon Feb 16 13:34:56 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Bellon, S F.
- Dussault, I.
- Kaplan-Lefko, P.
- Moriguchi, J.
- Yang, Y.
- Zhang, Y.
- Atp-binding
- C-met
- Glycoprotein
- Membrane
- Nucleotide-binding
- Phosphorylation
- Proto-oncogene
- Receptor tyrosine kinase
- Su11274
- Transferase
- Transmembrane
- Tyrosine-protein kinase