1kaw: Difference between revisions

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[[Image:1kaw.jpg|left|200px]]<br /><applet load="1kaw" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1kaw.jpg|left|200px]]<br /><applet load="1kaw" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1kaw, resolution 2.9Å" />

'''STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)'''<br />

==Overview==

The crystal structure of the tetrameric DNA-binding domain of the, single-stranded DNA binding protein from Escherichia coli was determined, at a resolution of 2.9 A using multiwavelength anomalous dispersion. Each, monomer in the tetramer is topologically similar to an oligomer-binding, fold. Two monomers each contribute three beta-strands to a single, six-stranded beta-sheet to form a dimer. Two dimer-dimer interfaces are, observed within the crystal. One of these stabilizes the tetramer in, solution. The other interface promotes a superhelical structure within the, crystal that may reflect tetramer-tetramer interactions involved in the, positive cooperative binding of the single-stranded DNA-binding protein to, single-stranded DNA.

The crystal structure of the tetrameric DNA-binding domain of the single-stranded DNA binding protein from Escherichia coli was determined at a resolution of 2.9 A using multiwavelength anomalous dispersion. Each monomer in the tetramer is topologically similar to an oligomer-binding fold. Two monomers each contribute three beta-strands to a single six-stranded beta-sheet to form a dimer. Two dimer-dimer interfaces are observed within the crystal. One of these stabilizes the tetramer in solution. The other interface promotes a superhelical structure within the crystal that may reflect tetramer-tetramer interactions involved in the positive cooperative binding of the single-stranded DNA-binding protein to single-stranded DNA.

==About this Structure==

1KAW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1KAW OCA].

1KAW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAW OCA].

==Reference==

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[[Category: ssb]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20 19~~:00~~:37 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:32:00 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1kaw.jpg|left|200px]]<br /><applet load="1kaw" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1kaw.jpg|left|200px]]<br /><applet load="1kaw" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1kaw, resolution 2.9&Aring;" />
 '''STRUCTURE OF SINGLE STRANDED DNA BINDING PROTEIN (SSB)'''<br />
 ==Overview==
-The crystal structure of the tetrameric DNA-binding domain of the, single-stranded DNA binding protein from Escherichia coli was determined, at a resolution of 2.9 A using multiwavelength anomalous dispersion. Each, monomer in the tetramer is topologically similar to an oligomer-binding, fold. Two monomers each contribute three beta-strands to a single, six-stranded beta-sheet to form a dimer. Two dimer-dimer interfaces are, observed within the crystal. One of these stabilizes the tetramer in, solution. The other interface promotes a superhelical structure within the, crystal that may reflect tetramer-tetramer interactions involved in the, positive cooperative binding of the single-stranded DNA-binding protein to, single-stranded DNA.
+The crystal structure of the tetrameric DNA-binding domain of the single-stranded DNA binding protein from Escherichia coli was determined at a resolution of 2.9 A using multiwavelength anomalous dispersion. Each monomer in the tetramer is topologically similar to an oligomer-binding fold. Two monomers each contribute three beta-strands to a single six-stranded beta-sheet to form a dimer. Two dimer-dimer interfaces are observed within the crystal. One of these stabilizes the tetramer in solution. The other interface promotes a superhelical structure within the crystal that may reflect tetramer-tetramer interactions involved in the positive cooperative binding of the single-stranded DNA-binding protein to single-stranded DNA.
 ==About this Structure==
-KAW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1KAW OCA].
+KAW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KAW OCA].
 ==Reference==
@@ Line 19: / Line 19: @@
 [[Category: ssb]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 19:00:37 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:32:00 2008''