1rr8: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
1RR8 is a | 1RR8 is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RR8 OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:15165849</ref><references group="xtra"/> | |||
[[Category: DNA topoisomerase]] | [[Category: DNA topoisomerase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Burgin, A B.]] | [[Category: Burgin, A B.]] | ||
[[Category: Chrencik, J E.]] | [[Category: Chrencik, J E.]] | ||
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[[Category: Topotecan]] | [[Category: Topotecan]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 14:51:35 2009'' | ||
Revision as of 12:51, 16 February 2009
Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I
Template:ABSTRACT PUBMED 15165849
Disease
Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[126420]
About this Structure
1RR8 is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chrencik JE, Staker BL, Burgin AB, Pourquier P, Pommier Y, Stewart L, Redinbo MR. Mechanisms of camptothecin resistance by human topoisomerase I mutations. J Mol Biol. 2004 Jun 11;339(4):773-84. PMID:15165849 doi:https://dx.doi.org/10.1016/j.jmb.2004.03.077
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