1rrj: Difference between revisions

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==About this Structure==
==About this Structure==
1RRJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRJ OCA].  
1RRJ is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RRJ OCA].  


==Reference==
==Reference==
Mechanisms of camptothecin resistance by human topoisomerase I mutations., Chrencik JE, Staker BL, Burgin AB, Pourquier P, Pommier Y, Stewart L, Redinbo MR, J Mol Biol. 2004 Jun 11;339(4):773-84. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15165849 15165849]
<ref group="xtra">PMID:15165849</ref><references group="xtra"/>
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Burgin, A B.]]
[[Category: Burgin, A B.]]
[[Category: Chrencik, J E.]]
[[Category: Chrencik, J E.]]
Line 40: Line 39:
[[Category: X-ray crystallography]]
[[Category: X-ray crystallography]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 17:56:49 2009''

Revision as of 15:56, 16 February 2009

File:1rrj.png

Template:STRUCTURE 1rrj

Structural Mechanisms of Camptothecin Resistance by Mutations in Human Topoisomerase I

Template:ABSTRACT PUBMED 15165849

Disease

Known disease associated with this structure: DNA topoisomerase I, camptothecin-resistant OMIM:[126420]

About this Structure

1RRJ is a 3 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Chrencik JE, Staker BL, Burgin AB, Pourquier P, Pommier Y, Stewart L, Redinbo MR. Mechanisms of camptothecin resistance by human topoisomerase I mutations. J Mol Biol. 2004 Jun 11;339(4):773-84. PMID:15165849 doi:https://dx.doi.org/10.1016/j.jmb.2004.03.077

Page seeded by OCA on Mon Feb 16 17:56:49 2009

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