1pwu: Difference between revisions

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{{Seed}}
[[Image:1pwu.png|left|200px]]
[[Image:1pwu.png|left|200px]]


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===Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.===
===Crystal Structure of Anthrax Lethal Factor complexed with (3-(N-hydroxycarboxamido)-2-isobutylpropanoyl-Trp-methylamide), a known small molecule inhibitor of matrix metalloproteases.===


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{{ABSTRACT_PUBMED_14718924}}


==About this Structure==
==About this Structure==
1PWU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWU OCA].  
[[1pwu]] is a 2 chain structure of [[Anthrax Lethal Factor]] with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PWU OCA].  
 
==See Also==
*[[Anthrax Lethal Factor|Anthrax Lethal Factor]]


==Reference==
==Reference==
The structural basis for substrate and inhibitor selectivity of the anthrax lethal factor., Turk BE, Wong TY, Schwarzenbacher R, Jarrell ET, Leppla SH, Collier RJ, Liddington RC, Cantley LC, Nat Struct Mol Biol. 2004 Jan;11(1):60-6. Epub 2003 Dec 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14718924 14718924]
<ref group="xtra">PMID:014718924</ref><references group="xtra"/>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Single protein]]
[[Category: Liddington, R C.]]
[[Category: Liddington, R C.]]
[[Category: Schwarzenbacher, R.]]
[[Category: Schwarzenbacher, R.]]
[[Category: Wong, T Y.]]
[[Category: Wong, T Y.]]
[[Category: Anthrax toxin]]
[[Category: Anthrax toxin]]
[[Category: Hydrolase]]
[[Category: Hydroxamic acid.]]
[[Category: Hydroxamic acid.]]
[[Category: Lethal factor]]
[[Category: Lethal factor]]
[[Category: Small molecule peptidic inhibitor]]
[[Category: Small molecule peptidic inhibitor]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 00:32:37 2008''