2a0q: Difference between revisions

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==About this Structure==
==About this Structure==
2A0Q is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A0Q OCA].  
2A0Q is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A0Q OCA].  


==Reference==
==Reference==
Thrombin functions through its RGD sequence in a non-canonical conformation., Papaconstantinou ME, Carrell CJ, Pineda AO, Bobofchak KM, Mathews FS, Flordellis CS, Maragoudakis ME, Tsopanoglou NE, Di Cera E, J Biol Chem. 2005 Aug 19;280(33):29393-6. Epub 2005 Jul 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15998637 15998637]
<ref group="xtra">PMID:15998637</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Bobofchak, K M.]]
[[Category: Bobofchak, K M.]]
Line 41: Line 40:
[[Category: Serine protease]]
[[Category: Serine protease]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 04:09:57 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 23:49:54 2009''

Revision as of 21:49, 16 February 2009

File:2a0q.png

Template:STRUCTURE 2a0q

Structure of thrombin in 400 mM potassium chloride

Template:ABSTRACT PUBMED 15998637

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

2A0Q is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Papaconstantinou ME, Carrell CJ, Pineda AO, Bobofchak KM, Mathews FS, Flordellis CS, Maragoudakis ME, Tsopanoglou NE, Di Cera E. Thrombin functions through its RGD sequence in a non-canonical conformation. J Biol Chem. 2005 Aug 19;280(33):29393-6. Epub 2005 Jul 5. PMID:15998637 doi:10.1074/jbc.C500248200

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