1s8o: Difference between revisions

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==About this Structure==
==About this Structure==
1S8O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8O OCA].  
1S8O is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S8O OCA].  


==Reference==
==Reference==
Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis., Gomez GA, Morisseau C, Hammock BD, Christianson DW, Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15096040 15096040]
<ref group="xtra">PMID:15096040</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Microsomal epoxide hydrolase]]
[[Category: Microsomal epoxide hydrolase]]
[[Category: Single protein]]
[[Category: Christianson, D W.]]
[[Category: Christianson, D W.]]
[[Category: Gomez, G A.]]
[[Category: Gomez, G A.]]
Line 36: Line 35:
[[Category: Domain-swapped dimer]]
[[Category: Domain-swapped dimer]]


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Revision as of 22:11, 16 February 2009

File:1s8o.png


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1s8o, resolution 2.60Å (default scene)
Ligands: P6G
Gene: EPHX2 (Homo sapiens)
Activity: Hydrolase, with EC number and 3.3.2.10 3.3.2.9 and 3.3.2.10
Related: 1vj5
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Human soluble Epoxide Hydrolase

Template:ABSTRACT PUBMED 15096040

Disease

Known disease associated with this structure: Hypercholesterolemia, familial, due to LDLR defect, modifier of OMIM:[132811]

About this Structure

1S8O is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gomez GA, Morisseau C, Hammock BD, Christianson DW. Structure of human epoxide hydrolase reveals mechanistic inferences on bifunctional catalysis in epoxide and phosphate ester hydrolysis. Biochemistry. 2004 Apr 27;43(16):4716-23. PMID:15096040 doi:10.1021/bi036189j

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