1lqa: Difference between revisions

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New page: left|200px<br /><applet load="1lqa" size="450" color="white" frame="true" align="right" spinBox="true" caption="1lqa, resolution 1.604Å" /> '''TAS PROTEIN FROM ES...
 
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[[Image:1lqa.jpg|left|200px]]<br /><applet load="1lqa" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:1lqa.jpg|left|200px]]<br /><applet load="1lqa" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="1lqa, resolution 1.604&Aring;" />
caption="1lqa, resolution 1.604&Aring;" />
'''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH'''<br />
'''TAS PROTEIN FROM ESCHERICHIA COLI IN COMPLEX WITH NADPH'''<br />


==Overview==
==Overview==
BACKGROUND: The protein encoded by the gene ybgI was chosen as a target, for a structural genomics project emphasizing the relation of protein, structure to function. RESULTS: The structure of the ybgI protein is a, toroid composed of six polypeptide chains forming a trimer of dimers. Each, polypeptide chain binds two metal ions on the inside of the toroid., CONCLUSION: The toroidal structure is comparable to that of some proteins, that are involved in DNA metabolism. The di-nuclear metal site could imply, that the specific function of this protein is as a hydrolase-oxidase, enzyme.
BACKGROUND: The protein encoded by the gene ybgI was chosen as a target for a structural genomics project emphasizing the relation of protein structure to function. RESULTS: The structure of the ybgI protein is a toroid composed of six polypeptide chains forming a trimer of dimers. Each polypeptide chain binds two metal ions on the inside of the toroid. CONCLUSION: The toroidal structure is comparable to that of some proteins that are involved in DNA metabolism. The di-nuclear metal site could imply that the specific function of this protein is as a hydrolase-oxidase enzyme.


==About this Structure==
==About this Structure==
1LQA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with NDP as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1LQA OCA].  
1LQA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=NDP:'>NDP</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LQA OCA].  


==Reference==
==Reference==
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Camerini-Otero, R.D.]]
[[Category: Camerini-Otero, R D.]]
[[Category: Gilliland, G.L.]]
[[Category: Gilliland, G L.]]
[[Category: Howard, A.J.]]
[[Category: Howard, A J.]]
[[Category: Khil, P.P.]]
[[Category: Khil, P P.]]
[[Category: Obmolova, G.]]
[[Category: Obmolova, G.]]
[[Category: S2F, Structure.2.Function.Project.]]
[[Category: S2F, Structure 2.Function Project.]]
[[Category: Teplyakov, A.]]
[[Category: Teplyakov, A.]]
[[Category: NDP]]
[[Category: NDP]]
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[[Category: tim barrel]]
[[Category: tim barrel]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 20:46:35 2007''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:47:22 2008''