3bef: Difference between revisions

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==About this Structure==
==About this Structure==
3BEF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEF OCA].  
3BEF is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BEF OCA].  


==Reference==
==Reference==
Structural identification of the pathway of long-range communication in an allosteric enzyme., Gandhi PS, Chen Z, Mathews FS, Di Cera E, Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18250335 18250335]
<ref group="xtra">PMID:18250335</ref><ref group="xtra">PMID:15152000</ref><ref group="xtra">PMID:16954215</ref><references group="xtra"/>
 
Molecular dissection of Na+ binding to thrombin., Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E, J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15152000 15152000]
 
Crystal structure of thrombin in a self-inhibited conformation., Pineda AO, Chen ZW, Bah A, Garvey LC, Mathews FS, Di Cera E, J Biol Chem. 2006 Oct 27;281(43):32922-8. Epub 2006 Sep 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16954215 16954215]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Thrombin]]
[[Category: Thrombin]]
[[Category: Bah, A.]]
[[Category: Bah, A.]]
Line 59: Line 54:
[[Category: Zymogen]]
[[Category: Zymogen]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 09:33:57 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 06:04:47 2009''

Revision as of 04:04, 17 February 2009

File:3bef.png

Template:STRUCTURE 3bef

Crystal structure of thrombin bound to the extracellular fragment of PAR1

Template:ABSTRACT PUBMED 18250335

Disease

Known disease associated with this structure: Dysprothrombinemia OMIM:[176930], Hyperprothrombinemia OMIM:[176930], Hypoprothrombinemia OMIM:[176930]

About this Structure

3BEF is a 6 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Gandhi PS, Chen Z, Mathews FS, Di Cera E. Structural identification of the pathway of long-range communication in an allosteric enzyme. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):1832-7. Epub 2008 Feb 4. PMID:18250335
  2. Pineda AO, Carrell CJ, Bush LA, Prasad S, Caccia S, Chen ZW, Mathews FS, Di Cera E. Molecular dissection of Na+ binding to thrombin. J Biol Chem. 2004 Jul 23;279(30):31842-53. Epub 2004 May 19. PMID:15152000 doi:https://dx.doi.org/10.1074/jbc.M401756200
  3. Pineda AO, Chen ZW, Bah A, Garvey LC, Mathews FS, Di Cera E. Crystal structure of thrombin in a self-inhibited conformation. J Biol Chem. 2006 Oct 27;281(43):32922-8. Epub 2006 Sep 5. PMID:16954215 doi:https://dx.doi.org/10.1074/jbc.M605530200

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