2gqv: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
[[2gqv]] is a 1 chain structure of [[Dihydrofolate reductase]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GQV OCA]. | |||
==See Also== | |||
*[[Dihydrofolate reductase]] | |||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:16790925</ref><ref group="xtra">PMID:7583655</ref><ref group="xtra">PMID:3530319</ref><references group="xtra"/> | |||
[[Category: Dihydrofolate reductase]] | [[Category: Dihydrofolate reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Narayana, N.]] | [[Category: Narayana, N.]] | ||
[[Category: Anisotropic refinement]] | [[Category: Anisotropic refinement]] | ||
[[Category: Atomic-resolution structure]] | [[Category: Atomic-resolution structure]] | ||
[[Category: Folate metabolism]] | [[Category: Folate metabolism]] | ||
[[Category: Oxidoreductase]] | |||
[[Category: Plasmid-encoded r67 dhfr]] | [[Category: Plasmid-encoded r67 dhfr]] | ||
[[Category: Tmp-resistant dhfr]] | [[Category: Tmp-resistant dhfr]] | ||
Revision as of 23:29, 26 December 2010
High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site
Template:ABSTRACT PUBMED 16790925
About this Structure
2gqv is a 1 chain structure of Dihydrofolate reductase with sequence from Escherichia coli. Full crystallographic information is available from OCA.
See Also
Reference
- Narayana N. High-resolution structure of a plasmid-encoded dihydrofolate reductase: pentagonal network of water molecules in the D2-symmetric active site. Acta Crystallogr D Biol Crystallogr. 2006 Jul;62(Pt 7):695-706. Epub 2006, Jun 20. PMID:16790925 doi:S0907444906014764
- Narayana N, Matthews DA, Howell EE, Nguyen-huu X. A plasmid-encoded dihydrofolate reductase from trimethoprim-resistant bacteria has a novel D2-symmetric active site. Nat Struct Biol. 1995 Nov;2(11):1018-25. PMID:7583655
- Matthews DA, Smith SL, Baccanari DP, Burchall JJ, Oatley SJ, Kraut J. Crystal structure of a novel trimethoprim-resistant dihydrofolate reductase specified in Escherichia coli by R-plasmid R67. Biochemistry. 1986 Jul 29;25(15):4194-204. PMID:3530319
