1mvp: Difference between revisions

Line 1:

[[Image:1mvp.gif|left|200px]]<br /><applet load="1mvp" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1mvp.gif|left|200px]]<br /><applet load="1mvp" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1mvp, resolution 2.2Å" />

'''STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS'''<br />

==Overview==

The structure of the retroviral proteinase from avian myeloblastosis, associated virus (MAV) has been determined and refined at 2.2 A, resolution. This structure is compared with those of homologous, proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type, 1 virus (HIV). Through comparison with the structure of a, proteinase-inhibitor complex from HIV, a model of a complex between MAV, proteinase and a peptide substrate has been generated. Examination of this, model suggests structural basis for the diverse specifications of viral, proteinases.

The structure of the retroviral proteinase from avian myeloblastosis associated virus (MAV) has been determined and refined at 2.2 A resolution. This structure is compared with those of homologous proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type 1 virus (HIV). Through comparison with the structure of a proteinase-inhibitor complex from HIV, a model of a complex between MAV proteinase and a peptide substrate has been generated. Examination of this model suggests structural basis for the diverse specifications of viral proteinases.

==About this Structure==

1MVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Avian_myeloblastosis_associated_virus Avian myeloblastosis associated virus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1MVP OCA].

1MVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Avian_myeloblastosis_associated_virus Avian myeloblastosis associated virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVP OCA].

==Reference==

Line 13:

[[Category: Avian myeloblastosis associated virus]]

[[Category: Single protein]]

[[Category: Foundling, S.I.]]

[[Category: Foundling, S I.]]

[[Category: Ohlendorf, D.H.]]

[[Category: Ohlendorf, D H.]]

[[Category: Salemme, F.R.]]

[[Category: Salemme, F R.]]

[[Category: hydrolase(aspartic proteinase)]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20~~ 21:44:~~24 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:59:31 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1mvp.gif|left|200px]]<br /><applet load="1mvp" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1mvp.gif|left|200px]]<br /><applet load="1mvp" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1mvp, resolution 2.2&Aring;" />
 '''STRUCTURAL STUDIES OF THE RETROVIRAL PROTEINASE FROM AVIAN MYELOBLASTOSIS ASSOCIATED VIRUS'''<br />
 ==Overview==
-The structure of the retroviral proteinase from avian myeloblastosis, associated virus (MAV) has been determined and refined at 2.2 A, resolution. This structure is compared with those of homologous, proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type, 1 virus (HIV). Through comparison with the structure of a, proteinase-inhibitor complex from HIV, a model of a complex between MAV, proteinase and a peptide substrate has been generated. Examination of this, model suggests structural basis for the diverse specifications of viral, proteinases.
+The structure of the retroviral proteinase from avian myeloblastosis associated virus (MAV) has been determined and refined at 2.2 A resolution. This structure is compared with those of homologous proteinases from Rous sarcoma virus (RSV) and human immunodeficiency type 1 virus (HIV). Through comparison with the structure of a proteinase-inhibitor complex from HIV, a model of a complex between MAV proteinase and a peptide substrate has been generated. Examination of this model suggests structural basis for the diverse specifications of viral proteinases.
 ==About this Structure==
-MVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Avian_myeloblastosis_associated_virus Avian myeloblastosis associated virus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1MVP OCA].
+MVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Avian_myeloblastosis_associated_virus Avian myeloblastosis associated virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MVP OCA].
 ==Reference==
@@ Line 13: / Line 13: @@
 [[Category: Avian myeloblastosis associated virus]]
 [[Category: Single protein]]
-[[Category: Foundling, S.I.]]
+[[Category: Foundling, S I.]]
-[[Category: Ohlendorf, D.H.]]
+[[Category: Ohlendorf, D H.]]
-[[Category: Salemme, F.R.]]
+[[Category: Salemme, F R.]]
 [[Category: hydrolase(aspartic proteinase)]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 21:44:24 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:59:31 2008''