2fm2: Difference between revisions

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{{Seed}}
[[Image:2fm2.png|left|200px]]
[[Image:2fm2.png|left|200px]]


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{{STRUCTURE_2fm2|  PDB=2fm2  |  SCENE=  }}  
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===HCV NS3-4A protease domain complexed with a ketoamide inhibitor, SCH446211===
===HCV NS3-4A protease domain complexed with a ketoamide inhibitor, SCH446211===


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{{ABSTRACT_PUBMED_16352601}}
{{ABSTRACT_PUBMED_16352601}}


==About this Structure==
==About this Structure==
2FM2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FM2 OCA].  
[[2fm2]] is a 4 chain structure of [[Helicase]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FM2 OCA].  
 
==See Also==
*[[Helicase|Helicase]]


==Reference==
==Reference==
Mutations conferring resistance to SCH6, a novel hepatitis C virus NS3/4A protease inhibitor. Reduced RNA replication fitness and partial rescue by second-site mutations., Yi M, Tong X, Skelton A, Chase R, Chen T, Prongay A, Bogen SL, Saksena AK, Njoroge FG, Veselenak RL, Pyles RB, Bourne N, Malcolm BA, Lemon SM, J Biol Chem. 2006 Mar 24;281(12):8205-15. Epub 2005 Dec 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16352601 16352601]
<ref group="xtra">PMID:016352601</ref><references group="xtra"/>
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: Single protein]]
[[Category: Bogen, S L.]]
[[Category: Bogen, S L.]]
[[Category: Bourne, N.]]
[[Category: Bourne, N.]]
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[[Category: Hcv]]
[[Category: Hcv]]
[[Category: Hepatitis c virus]]
[[Category: Hepatitis c virus]]
[[Category: Hydrolase]]
[[Category: Ketoamide inhibitor]]
[[Category: Ketoamide inhibitor]]
[[Category: Ns3/4a protease]]
[[Category: Ns3/4a protease]]
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Retrieved from "https://proteopedia.org/2fm2"