2o8d: Difference between revisions

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==About this Structure==
==About this Structure==
2O8D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8D OCA].  
2O8D is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8D OCA].  


==Reference==
==Reference==
Structure of the human MutSalpha DNA lesion recognition complex., Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS, Mol Cell. 2007 May 25;26(4):579-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17531815 17531815]
<ref group="xtra">PMID:17531815</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Beese, L S.]]
[[Category: Beese, L S.]]
[[Category: Changela, A.]]
[[Category: Changela, A.]]
Line 41: Line 40:
[[Category: Somatic hypermutation]]
[[Category: Somatic hypermutation]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 14:28:37 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 10:35:05 2009''

Revision as of 08:35, 17 February 2009

File:2o8d.png

Template:STRUCTURE 2o8d

human MutSalpha (MSH2/MSH6) bound to ADP and a G dU mispair

Template:ABSTRACT PUBMED 17531815

Disease

Known disease associated with this structure: Colorectal cancer, hereditary nonpolyposis, type 1 OMIM:[609309], Mismatch repair cancer syndrome OMIM:[609309], Muir-Torre syndrome OMIM:[609309]

About this Structure

2O8D is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Warren JJ, Pohlhaus TJ, Changela A, Iyer RR, Modrich PL, Beese LS. Structure of the human MutSalpha DNA lesion recognition complex. Mol Cell. 2007 May 25;26(4):579-92. PMID:17531815 doi:10.1016/j.molcel.2007.04.018

Page seeded by OCA on Tue Feb 17 10:35:05 2009

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