2b7a: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
2B7A is a | 2B7A is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2B7A OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:16174768</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Bamert, R.]] | [[Category: Bamert, R.]] | ||
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[[Category: Kinase]] | [[Category: Kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:52:11 2009'' | ||
Revision as of 10:52, 17 February 2009
The structural basis of Janus Kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor
Template:ABSTRACT PUBMED 16174768
Disease
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]
About this Structure
2B7A is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lucet IS, Fantino E, Styles M, Bamert R, Patel O, Broughton SE, Walter M, Burns CJ, Treutlein H, Wilks AF, Rossjohn J. The structural basis of Janus kinase 2 inhibition by a potent and specific pan-Janus kinase inhibitor. Blood. 2006 Jan 1;107(1):176-83. Epub 2005 Sep 20. PMID:16174768 doi:https://dx.doi.org/10.1182/blood-2005-06-2413
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