1nq3: Difference between revisions

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[[Image:1nq3.gif|left|200px]]<br /><applet load="1nq3" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1nq3.gif|left|200px]]<br /><applet load="1nq3" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1nq3, resolution 2.2Å" />

'''Crystal structure of the mammalian tumor associated antigen UK114'''<br />

==Overview==

The tumour-associated antigen UK114, isolated from goat liver, belongs to, the YER057c/YIL051c/YjgF protein family, which has members in both the, prokaryotes and eukaryotes. The crystal structure of a mammalian, representative, goat UK114, was determined, revealing a trimeric, arrangement in the crystal. It was confirmed by ultracentrifugation that, UK114 is a trimer in solution. These results are in agreement with the, published structures of homologues from unicellular organisms, but, contrast with those reported for the rat homologue of UK114, for which a, dimeric quaternary structure was proposed.

The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.

==About this Structure==

1NQ3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1NQ3 OCA].

1NQ3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ3 OCA].

==Reference==

Line 15:

[[Category: Briand, C.]]

[[Category: Deriu, D.]]

[[Category: Grutter, M.G.]]

[[Category: Grutter, M G.]]

[[Category: Mistiniene, E.]]

[[Category: Naktinis, V.]]

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[[Category: yer057c/yil051c/yjgf protein family]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20 22~~:28:~~43 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:08:49 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1nq3.gif|left|200px]]<br /><applet load="1nq3" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1nq3.gif|left|200px]]<br /><applet load="1nq3" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1nq3, resolution 2.2&Aring;" />
 '''Crystal structure of the mammalian tumor associated antigen UK114'''<br />
 ==Overview==
-The tumour-associated antigen UK114, isolated from goat liver, belongs to, the YER057c/YIL051c/YjgF protein family, which has members in both the, prokaryotes and eukaryotes. The crystal structure of a mammalian, representative, goat UK114, was determined, revealing a trimeric, arrangement in the crystal. It was confirmed by ultracentrifugation that, UK114 is a trimer in solution. These results are in agreement with the, published structures of homologues from unicellular organisms, but, contrast with those reported for the rat homologue of UK114, for which a, dimeric quaternary structure was proposed.
+The tumour-associated antigen UK114, isolated from goat liver, belongs to the YER057c/YIL051c/YjgF protein family, which has members in both the prokaryotes and eukaryotes. The crystal structure of a mammalian representative, goat UK114, was determined, revealing a trimeric arrangement in the crystal. It was confirmed by ultracentrifugation that UK114 is a trimer in solution. These results are in agreement with the published structures of homologues from unicellular organisms, but contrast with those reported for the rat homologue of UK114, for which a dimeric quaternary structure was proposed.
 ==About this Structure==
-NQ3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NQ3 OCA].
+NQ3 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NQ3 OCA].
 ==Reference==
@@ Line 15: / Line 15: @@
 [[Category: Briand, C.]]
 [[Category: Deriu, D.]]
-[[Category: Grutter, M.G.]]
+[[Category: Grutter, M G.]]
 [[Category: Mistiniene, E.]]
 [[Category: Naktinis, V.]]
@@ Line 24: / Line 24: @@
 [[Category: yer057c/yil051c/yjgf protein family]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 22:28:43 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:08:49 2008''