1ntn: Difference between revisions

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[[Image:1ntn.gif|left|200px]]<br /><applet load="1ntn" size="~~450~~" color="white" frame="true" align="right" spinBox="true"

[[Image:1ntn.gif|left|200px]]<br /><applet load="1ntn" size="350" color="white" frame="true" align="right" spinBox="true"

caption="1ntn, resolution 1.9Å" />

'''THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION'''<br />

==Overview==

Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by, vapor diffusion in sitting drops. The crystals have cell dimensions of a =, 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1)., Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1), automatic diffractometer. The atomic structure of the toxin has been, determined by molecular replacement using the alpha-cobratoxin (alpha-CTX), as the search model. The position of 534 non-hydrogen protein atoms have, been determined. The model contains 65 water molecules. Refinement has led, to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary, structures of NTX-1 have been analyzed and a comparison with structure of, the alpha-CTX has been made.

Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by vapor diffusion in sitting drops. The crystals have cell dimensions of a = 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1). Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1) automatic diffractometer. The atomic structure of the toxin has been determined by molecular replacement using the alpha-cobratoxin (alpha-CTX) as the search model. The position of 534 non-hydrogen protein atoms have been determined. The model contains 65 water molecules. Refinement has led to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary structures of NTX-1 have been analyzed and a comparison with structure of the alpha-CTX has been made.

==About this Structure==

1NTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full crystallographic information is available from [http://~~ispc~~.weizmann.ac.il/oca-bin/ocashort?id=1NTN OCA].

1NTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTN OCA].

==Reference==

Line 14:

[[Category: Single protein]]

[[Category: Betzel, C.]]

[[Category: Mikhailov, A.M.]]

[[Category: Mikhailov, A M.]]

[[Category: Nickitenko, A.V.]]

[[Category: Nickitenko, A V.]]

[[Category: Vainshtein, B.K.]]

[[Category: Vainshtein, B K.]]

[[Category: Wilson, K.]]

[[Category: postsynaptic neurotoxin]]

''Page seeded by [http://~~ispc~~.weizmann.ac.il/oca OCA ] on ~~Tue Nov 20 22~~:32:~~51 2007~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:09:52 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1ntn.gif|left|200px]]<br /><applet load="1ntn" size="450" color="white" frame="true" align="right" spinBox="true"
+[[Image:1ntn.gif|left|200px]]<br /><applet load="1ntn" size="350" color="white" frame="true" align="right" spinBox="true"
 caption="1ntn, resolution 1.9&Aring;" />
 '''THE CRYSTAL STRUCTURE OF NEUROTOXIN-I FROM NAJA NAJA OXIANA AT 1.9 ANGSTROMS RESOLUTION'''<br />
 ==Overview==
-Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by, vapor diffusion in sitting drops. The crystals have cell dimensions of a =, 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1)., Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1), automatic diffractometer. The atomic structure of the toxin has been, determined by molecular replacement using the alpha-cobratoxin (alpha-CTX), as the search model. The position of 534 non-hydrogen protein atoms have, been determined. The model contains 65 water molecules. Refinement has led, to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary, structures of NTX-1 have been analyzed and a comparison with structure of, the alpha-CTX has been made.
+Neurotoxin-1 from Naja naja oxiana venom (NTX-1) has been crystallized by vapor diffusion in sitting drops. The crystals have cell dimensions of a = 25.2 A, b = 75.6 A, c = 35.9 A, and are in space group P2(1)2(1)2(1). Three-dimensional data to 1.9 A have been recorded by a Syntex P2(1) automatic diffractometer. The atomic structure of the toxin has been determined by molecular replacement using the alpha-cobratoxin (alpha-CTX) as the search model. The position of 534 non-hydrogen protein atoms have been determined. The model contains 65 water molecules. Refinement has led to an R-factor of 19.3% at 1.9 A resolution. The secondary and tertiary structures of NTX-1 have been analyzed and a comparison with structure of the alpha-CTX has been made.
 ==About this Structure==
-NTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1NTN OCA].
+NTN is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Naja_oxiana Naja oxiana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NTN OCA].
 ==Reference==
@@ Line 14: / Line 14: @@
 [[Category: Single protein]]
 [[Category: Betzel, C.]]
-[[Category: Mikhailov, A.M.]]
+[[Category: Mikhailov, A M.]]
-[[Category: Nickitenko, A.V.]]
+[[Category: Nickitenko, A V.]]
-[[Category: Vainshtein, B.K.]]
+[[Category: Vainshtein, B K.]]
 [[Category: Wilson, K.]]
 [[Category: postsynaptic neurotoxin]]
-''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 22:32:51 2007''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:09:52 2008''