1zpc: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
1ZPC is a | 1ZPC is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZPC OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:16524727</ref><references group="xtra"/> | |||
[[Category: Coagulation factor XIa]] | [[Category: Coagulation factor XIa]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Abdel-Meguid, S S.]] | [[Category: Abdel-Meguid, S S.]] | ||
[[Category: Babine, R E.]] | [[Category: Babine, R E.]] | ||
| Line 49: | Line 48: | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 18:52:32 2009'' | ||
Revision as of 16:52, 17 February 2009
Crystal Structure of the Catalytic Domain of Coagulation Factor XI in Complex with 2-[2-(3-Chloro-phenyl)-2-hydroxy-acetylamino]-N-[4-guanidino-1-(thiazole-2-carbonyl)-butyl]-3-methyl-butyramide
Template:ABSTRACT PUBMED 16524727
Disease
Known disease associated with this structure: Factor XI deficiency, autosomal dominant OMIM:[264900], Factor XI deficiency, autosomal recessive OMIM:[264900]
About this Structure
1ZPC is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Deng H, Bannister TD, Jin L, Babine RE, Quinn J, Nagafuji P, Celatka CA, Lin J, Lazarova TI, Rynkiewicz MJ, Bibbins F, Pandey P, Gorga J, Meyers HV, Abdel-Meguid SS, Strickler JE. Synthesis, SAR exploration, and X-ray crystal structures of factor XIa inhibitors containing an alpha-ketothiazole arginine. Bioorg Med Chem Lett. 2006 Jun 1;16(11):3049-54. Epub 2006 Mar 9. PMID:16524727 doi:https://dx.doi.org/10.1016/j.bmcl.2006.02.052
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