1pqy: Difference between revisions

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New page: left|200px<br /><applet load="1pqy" size="450" color="white" frame="true" align="right" spinBox="true" caption="1pqy, resolution 2.35Å" /> '''Crystal structure of...
 
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[[Image:1pqy.gif|left|200px]]<br /><applet load="1pqy" size="450" color="white" frame="true" align="right" spinBox="true"  
[[Image:1pqy.gif|left|200px]]<br /><applet load="1pqy" size="350" color="white" frame="true" align="right" spinBox="true"  
caption="1pqy, resolution 2.35&Aring;" />
caption="1pqy, resolution 2.35&Aring;" />
'''Crystal structure of formyl-coA transferase yfdW from E. coli'''<br />
'''Crystal structure of formyl-coA transferase yfdW from E. coli'''<br />


==Overview==
==Overview==
Crystal structures are reported for free and coenzyme A (CoA) bound forms, of the YfdW protein from Escherichia coli, a representative type III CoA, transferase. The structures reveal a two-domain protomer with interdomain, connections forming a ring-like structure with a large central hole. Two, protomers associate to form a highly intertwined dimer in which the hole, of each ring is filled by the partner molecule. Each protomer binds a, single CoA molecule and these CoA-binding sites are distant from one, another in the dimer.
Crystal structures are reported for free and coenzyme A (CoA) bound forms of the YfdW protein from Escherichia coli, a representative type III CoA transferase. The structures reveal a two-domain protomer with interdomain connections forming a ring-like structure with a large central hole. Two protomers associate to form a highly intertwined dimer in which the hole of each ring is filled by the partner molecule. Each protomer binds a single CoA molecule and these CoA-binding sites are distant from one another in the dimer.


==About this Structure==
==About this Structure==
1PQY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1PQY OCA].  
1PQY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PQY OCA].  


==Reference==
==Reference==
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Burley, S.K.]]
[[Category: Burley, S K.]]
[[Category: Gogos, A.]]
[[Category: Gogos, A.]]
[[Category: Gorman, J.]]
[[Category: Gorman, J.]]
[[Category: NYSGXRC, New.York.Structural.GenomiX.Research.Consortium.]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Shapiro, L.]]
[[Category: Shapiro, L.]]
[[Category: intertwined dimer]]
[[Category: intertwined dimer]]
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[[Category: structural genomics]]
[[Category: structural genomics]]


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 00:02:34 2007''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:31:39 2008''