2ec8: Difference between revisions

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==About this Structure==
==About this Structure==
2EC8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EC8 OCA].  
2EC8 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EC8 OCA].  


==Reference==
==Reference==
Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor., Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J, Cell. 2007 Jul 27;130(2):323-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17662946 17662946]
<ref group="xtra">PMID:17662946</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Receptor protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Lax, I.]]
[[Category: Lax, I.]]
[[Category: Mandiyan, V.]]
[[Category: Mandiyan, V.]]
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[[Category: Transferase]]
[[Category: Transferase]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 10:20:55 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:06:19 2009''

Revision as of 02:06, 18 February 2009

File:2ec8.png

Template:STRUCTURE 2ec8

Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit

Template:ABSTRACT PUBMED 17662946

Disease

Known disease associated with this structure: Gastrointestinal stromal tumor, somatic OMIM:[164920], Germ cell tumors OMIM:[164920], Leukemia, acute myeloid OMIM:[164920], Mast cell leukemia OMIM:[164920], Mastocytosis with associated hematologic disorder OMIM:[164920], Piebaldism OMIM:[164920]

About this Structure

2EC8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Yuzawa S, Opatowsky Y, Zhang Z, Mandiyan V, Lax I, Schlessinger J. Structural basis for activation of the receptor tyrosine kinase KIT by stem cell factor. Cell. 2007 Jul 27;130(2):323-34. PMID:17662946 doi:https://dx.doi.org/10.1016/j.cell.2007.05.055

Page seeded by OCA on Wed Feb 18 04:06:19 2009

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