2fir: Difference between revisions

Revision as of 04:43, 18 February 2009

This article has been automatically seeded. Changes to this page should pertain to the PDB entry only and not to the protein or biomolecule in general.

File:2fir.png

2fir, resolution 2.00Å (default scene)

Ligands:

0G7, CA, CL, FUC, GLC, MG, NA, ZN

Non-Standard Residues:

CGU

Gene:

F7 (Homo sapiens), F3 (Homo sapiens)

Activity:

Coagulation factor VIIa, with EC number 3.4.21.21

Related:

1dan, 2a2q, 2aer, 2b8o

Structural annotation:
Resources:	CATH : 2Firh02, 2Firh01, 2Firt02, 2Firt01 InterPro : Ipr001314, Ipr018114, Ipr001254, Ipr000742, Ipr000294, Ipr000152, Ipr018097, Ipr017857, Ipr013032, Ipr012224, Ipr009003, Ipr001881, Ipr016354, Ipr015373, Ipr013783, Ipr003961, Ipr001187 Pfam : PF00089, PF00008, PF00594, PF09294, PF01108 SCOP : d2firh1, d2firl1, d2firl3, d2firl2, d2firt1, d2firt2

Evolutionary conservation:

Toggle Conservation Colors:

Rows = identical sequences:

Further Information:

Caveats,

Explanation,
Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

Crystal structure of DFPR-VIIa/sTF

Template:ABSTRACT PUBMED 16757484

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this Structure

2FIR is a 4 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200

Page seeded by OCA on Wed Feb 18 06:43:37 2009

Proteopedia Page Contributors and Editors (what is this?)

OCA

[1] Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K. High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa. J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:16757484 doi:10.1074/jbc.M509971200

@@ Line 23: / Line 23: @@
 ==About this Structure==
-FIR is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIR OCA].
+FIR is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FIR OCA].
 ==Reference==
-High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa., Bajaj SP, Schmidt AE, Agah S, Bajaj MS, Padmanabhan K, J Biol Chem. 2006 Aug 25;281(34):24873-88. Epub 2006 Jun 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16757484 16757484]
+<ref group="xtra">PMID:16757484</ref><references group="xtra"/>
 [[Category: Coagulation factor VIIa]]
 [[Category: Homo sapiens]]
-[[Category: Protein complex]]
 [[Category: Bajaj, M S.]]
 [[Category: Bajaj, S P.]]
@@ Line 45: / Line 44: @@
 [[Category: Zinc]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 13:27:34 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 06:43:37 2009''

2fir: Difference between revisions

Revision as of 04:43, 18 February 2009

Contents

Crystal structure of DFPR-VIIa/sTF

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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