3e8r: Difference between revisions

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New page: '''Unreleased structure''' The entry 3e8r is ON HOLD Authors: Orth, P. Description: Crystal structure of catalytic domain of TACE with hydroxamate inhibitor ''Page seeded by [http://o...
 
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'''Unreleased structure'''
{{Seed}}
[[Image:3e8r.jpg|left|200px]]


The entry 3e8r is ON HOLD
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{{STRUCTURE_3e8r|  PDB=3e8r |  SCENE=  }}


Authors: Orth, P.
===Crystal structure of catalytic domain of TACE with hydroxamate inhibitor===


Description: Crystal structure of catalytic domain of TACE with hydroxamate inhibitor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 27 11:01:34 2008''
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{{ABSTRACT_PUBMED_18835710}}
 
==About this Structure==
3E8R is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E8R OCA].
 
==Reference==
Discovery of novel hydroxamates as highly potent tumor necrosis factor-alpha converting enzyme inhibitors. Part II: Optimization of the S3' pocket., Mazzola RD Jr, Zhu Z, Sinning L, McKittrick B, Lavey B, Spitler J, Kozlowski J, Neng-Yang S, Zhou G, Guo Z, Orth P, Madison V, Sun J, Lundell D, Niu X, Bioorg Med Chem Lett. 2008 Sep 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18835710 18835710]
[[Category: ADAM 17 endopeptidase]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Orth, P.]]
[[Category: Alternative splicing]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Membrane]]
[[Category: Metal-binding]]
[[Category: Metalloprotease]]
[[Category: Notch signaling pathway]]
[[Category: Phosphoprotein]]
[[Category: Protease]]
[[Category: Sh3-binding]]
[[Category: Tace adam17 zn-endopeptidase]]
[[Category: Transmembrane]]
[[Category: Zinc]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 10:51:38 2008''