3bys: Difference between revisions

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[[Image:3bys.~~jpg~~|left|200px]]

[[Image:3bys.png|left|200px]]

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===co-crystal structure of Lck and aminopyrimidine amide 10b===

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The line below this paragraph, {{ABSTRACT_PUBMED_18321037}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 18321037 is the PubMed ID number.

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==Disease==

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==About this Structure==

3BYS is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYS OCA].

3BYS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYS OCA].

==Reference==

Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation., DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X, J Med Chem. 2008 Mar 27;51(6):1681-94. Epub 2008 Mar 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18321037 18321037]

[[Category: Homo sapiens]]

[[Category: Non-specific protein-tyrosine kinase]]

~~[[Category: Single protein]]~~

[[Category: Huang, X.]]

[[Category: Alternative splicing]]

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[[Category: Tyrosine-protein kinase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 17~~ 14:~~27:44~~ 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 09:14:01 2008''

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@@ Line 1: / Line 1: @@
 {{Seed}}
-[[Image:3bys.jpg|left|200px]]
+[[Image:3bys.png|left|200px]]
 <!--
@@ Line 12: / Line 12: @@
 ===co-crystal structure of Lck and aminopyrimidine amide 10b===
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18321037}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18321037 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18321037}}
 ==Disease==
@@ Line 17: / Line 23: @@
 ==About this Structure==
-BYS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYS OCA].
+BYS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BYS OCA].
+==Reference==
+Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation., DiMauro EF, Newcomb J, Nunes JJ, Bemis JE, Boucher C, Chai L, Chaffee SC, Deak HL, Epstein LF, Faust T, Gallant P, Gore A, Gu Y, Henkle B, Hsieh F, Huang X, Kim JL, Lee JH, Martin MW, McGowan DC, Metz D, Mohn D, Morgenstern KA, Oliveira-dos-Santos A, Patel VF, Powers D, Rose PE, Schneider S, Tomlinson SA, Tudor YY, Turci SM, Welcher AA, Zhao H, Zhu L, Zhu X, J Med Chem. 2008 Mar 27;51(6):1681-94. Epub 2008 Mar 6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18321037 18321037]
 [[Category: Homo sapiens]]
 [[Category: Non-specific protein-tyrosine kinase]]
-[[Category: Single protein]]
 [[Category: Huang, X.]]
 [[Category: Alternative splicing]]
@@ Line 42: / Line 50: @@
 [[Category: Tyrosine-protein kinase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 17 14:27:44 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 31 09:14:01 2008''