3efk: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

[[Image:3efk.jpg|left|200px]]

The ~~entry~~ 3efk ~~is ON HOLD~~

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~~Authors: Bellon, S.F., D'Angelo, N., Whittington, D., Dussault, I.~~

===Structure of c-Met with pyrimidone inhibitor 50===

~~Description: Structure of c-Met with pyrimidone inhibitor 50~~

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed ~~Sep 24 10~~:15:05 2008''

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==Disease==

Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]

==About this Structure==

3EFK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EFK OCA].

==Reference==

Design, synthesis, and biological evaluation of potent c-Met inhibitors., D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS, J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18763753 18763753]

[[Category: Homo sapiens]]

[[Category: Receptor protein-tyrosine kinase]]

[[Category: Single protein]]

[[Category: Angelo, N D.]]

[[Category: Bellon, S F.]]

[[Category: Dussault, I.]]

[[Category: Whittington, D.]]

[[Category: Alternative splicing]]

[[Category: Atp-binding]]

[[Category: C-met]]

[[Category: Chromosomal rearrangement]]

[[Category: Disease mutation]]

[[Category: Glycoprotein]]

[[Category: Kinase]]

[[Category: Kinase inhibitor pyrimidone]]

[[Category: Membrane]]

[[Category: Nucleotide-binding]]

[[Category: Phosphoprotein]]

[[Category: Polymorphism]]

[[Category: Proto-oncogene]]

[[Category: Receptor]]

[[Category: Transferase]]

[[Category: Transmembrane]]

[[Category: Tyrosine-protein kinase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:36:24 2008''

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{Seed}}
+[[Image:3efk.jpg|left|200px]]
-The entry 3efk is ON HOLD
+<!--
+The line below this paragraph, containing "STRUCTURE_3efk", creates the "Structure Box" on the page.
+You may change the PDB parameter (which sets the PDB file loaded into the applet)
+or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+or leave the SCENE parameter empty for the default display.
+-->
+{{STRUCTURE_3efk|  PDB=3efk  |  SCENE=  }}
-Authors: Bellon, S.F., D'Angelo, N., Whittington, D., Dussault, I.
+===Structure of c-Met with pyrimidone inhibitor 50===
-Description: Structure of c-Met with pyrimidone inhibitor 50
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 24 10:15:05 2008''
+<!--
+The line below this paragraph, {{ABSTRACT_PUBMED_18763753}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18763753 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18763753}}
+==Disease==
+Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Renal cell carcinoma, papillary, familial and sporadic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]], Autism, suseptibility to, 9 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=164860 164860]]
+==About this Structure==
+EFK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EFK OCA].
+==Reference==
+Design, synthesis, and biological evaluation of potent c-Met inhibitors., D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS, J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18763753 18763753]
+[[Category: Homo sapiens]]
+[[Category: Receptor protein-tyrosine kinase]]
+[[Category: Single protein]]
+[[Category: Angelo, N D.]]
+[[Category: Bellon, S F.]]
+[[Category: Dussault, I.]]
+[[Category: Whittington, D.]]
+[[Category: Alternative splicing]]
+[[Category: Atp-binding]]
+[[Category: C-met]]
+[[Category: Chromosomal rearrangement]]
+[[Category: Disease mutation]]
+[[Category: Glycoprotein]]
+[[Category: Kinase]]
+[[Category: Kinase inhibitor pyrimidone]]
+[[Category: Membrane]]
+[[Category: Nucleotide-binding]]
+[[Category: Phosphoprotein]]
+[[Category: Polymorphism]]
+[[Category: Proto-oncogene]]
+[[Category: Receptor]]
+[[Category: Transferase]]
+[[Category: Transmembrane]]
+[[Category: Tyrosine-protein kinase]]
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  8 09:36:24 2008''