1s7o: Difference between revisions
New page: left|200px<br /><applet load="1s7o" size="450" color="white" frame="true" align="right" spinBox="true" caption="1s7o, resolution 2.31Å" /> '''Crystal structure of... |
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[[Image:1s7o.gif|left|200px]]<br /><applet load="1s7o" size=" | [[Image:1s7o.gif|left|200px]]<br /><applet load="1s7o" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1s7o, resolution 2.31Å" /> | caption="1s7o, resolution 2.31Å" /> | ||
'''Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes'''<br /> | '''Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes'''<br /> | ||
==Overview== | ==Overview== | ||
The crystal structure of the putative DNA-binding protein SP_1288 | The crystal structure of the putative DNA-binding protein SP_1288 (gi/15675166, also listed as gi/28895954) from Streptococcus pyogenes has been determined by X-ray crystallography to a resolution of 2.3 A using anomalous diffraction data at the Se peak wavelength. SP_1288 belongs to a family of proteins whose cellular function is associated with the signal recognition particle; no structural information has been available until now about the members of the family. Crystallographic analysis revealed that the overall fold of SP_1288 consists exclusively of alpha-helices and that 75% of the structure has good similarity to domain 4 of the sigma subunit of RNA polymerase. This suggests its possible involvement in the biochemical function of transcription initiation, which includes interaction with DNA. | ||
==About this Structure== | ==About this Structure== | ||
1S7O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http:// | 1S7O is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes Streptococcus pyogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S7O OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Streptococcus pyogenes]] | [[Category: Streptococcus pyogenes]] | ||
[[Category: BSGC, Berkeley | [[Category: BSGC, Berkeley Structural Genomics Center.]] | ||
[[Category: DeGiovanni, A.]] | [[Category: DeGiovanni, A.]] | ||
[[Category: Kim, R.]] | [[Category: Kim, R.]] | ||
[[Category: Kim, S | [[Category: Kim, S H.]] | ||
[[Category: Oganesyan, V.]] | [[Category: Oganesyan, V.]] | ||
[[Category: Pufan, R.]] | [[Category: Pufan, R.]] | ||
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[[Category: x-rat crystallography]] | [[Category: x-rat crystallography]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:58:49 2008'' | ||
Revision as of 12:58, 21 February 2008
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Crystal structure of putative DNA binding protein SP_1288 from Streptococcus pygenes
Overview
The crystal structure of the putative DNA-binding protein SP_1288 (gi/15675166, also listed as gi/28895954) from Streptococcus pyogenes has been determined by X-ray crystallography to a resolution of 2.3 A using anomalous diffraction data at the Se peak wavelength. SP_1288 belongs to a family of proteins whose cellular function is associated with the signal recognition particle; no structural information has been available until now about the members of the family. Crystallographic analysis revealed that the overall fold of SP_1288 consists exclusively of alpha-helices and that 75% of the structure has good similarity to domain 4 of the sigma subunit of RNA polymerase. This suggests its possible involvement in the biochemical function of transcription initiation, which includes interaction with DNA.
About this Structure
1S7O is a Single protein structure of sequence from Streptococcus pyogenes. Full crystallographic information is available from OCA.
Reference
Structure of the putative DNA-binding protein SP_1288 from Streptococcus pyogenes., Oganesyan V, Pufan R, DeGiovanni A, Yokota H, Kim R, Kim SH, Acta Crystallogr D Biol Crystallogr. 2004 Jul;60(Pt 7):1266-71. Epub 2004, Jun 22. PMID:15213388
Page seeded by OCA on Thu Feb 21 14:58:49 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Single protein
- Streptococcus pyogenes
- BSGC, Berkeley Structural Genomics Center.
- DeGiovanni, A.
- Kim, R.
- Kim, S H.
- Oganesyan, V.
- Pufan, R.
- Yokota, H.
- Berkeley structural genomics center
- Bsgc
- Protein structure initiative
- Psi
- Putative dna binding protein; structural genomics
- Rna polymerase sigma factor
- Signal recognition particle
- Structure funded by nih
- Upf0122
- X-rat crystallography
