1sfo: Difference between revisions
From Proteopedia
Jump to navigationJump to search
New page: left|200px<br /><applet load="1sfo" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sfo, resolution 3.61Å" /> '''RNA POLYMERASE II ST... |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1sfo.gif|left|200px]]<br /><applet load="1sfo" size=" | [[Image:1sfo.gif|left|200px]]<br /><applet load="1sfo" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1sfo, resolution 3.61Å" /> | caption="1sfo, resolution 3.61Å" /> | ||
'''RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX'''<br /> | '''RNA POLYMERASE II STRAND SEPARATED ELONGATION COMPLEX'''<br /> | ||
==Overview== | ==Overview== | ||
The structure of an RNA polymerase II-transcribing complex has been | The structure of an RNA polymerase II-transcribing complex has been determined in the posttranslocation state, with a vacancy at the growing end of the RNA-DNA hybrid helix. At the opposite end of the hybrid helix, the RNA separates from the template DNA. This separation of nucleic acid strands is brought about by interaction with a set of proteins loops in a strand/loop network. Formation of the network must occur in the transition from abortive initiation to promoter escape. | ||
==About this Structure== | ==About this Structure== | ||
1SFO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with ZN and MG as [http://en.wikipedia.org/wiki/ligands ligands]. This structure | 1SFO is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=MG:'>MG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. This structure supersedes the now removed PDB entry 1R9R. Active as [http://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFO OCA]. | ||
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
[[Category: Bushnell, D | [[Category: Bushnell, D A.]] | ||
[[Category: Kornberg, R | [[Category: Kornberg, R D.]] | ||
[[Category: Westover, K | [[Category: Westover, K D.]] | ||
[[Category: MG]] | [[Category: MG]] | ||
[[Category: ZN]] | [[Category: ZN]] | ||
| Line 25: | Line 25: | ||
[[Category: transcription]] | [[Category: transcription]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:00:59 2008'' | ||
