1daj: Difference between revisions
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New page: left|200px<br /> <applet load="1daj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1daj, resolution 2.30Å" /> '''COMPARISON OF TERNA... |
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==About this Structure== | ==About this Structure== | ||
1DAJ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]] with NDP and MOT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/ ]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DAJ OCA]]. | 1DAJ is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Pneumocystis_carinii Pneumocystis carinii]] with NDP and MOT as [[http://en.wikipedia.org/wiki/ligands ligands]]. Active as [[http://en.wikipedia.org/wiki/Dihydrofolate_reductase Dihydrofolate reductase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.3 1.5.1.3]]. Structure known Active Site: S1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DAJ OCA]]. | ||
==Reference== | ==Reference== | ||
Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate., Cody V, Galitsky N, Luft JR, Pangborn W, Gangjee A, Devraj R, Queener SF, Blakley RL, Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):638-49. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299851 15299851] | Comparison of ternary complexes of Pneumocystis carinii and wild-type human dihydrofolate reductase with coenzyme NADPH and a novel classical antitumor furo[2,3-d]pyrimidine antifolate., Cody V, Galitsky N, Luft JR, Pangborn W, Gangjee A, Devraj R, Queener SF, Blakley RL, Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):638-49. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15299851 15299851] | ||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Pneumocystis carinii]] | [[Category: Pneumocystis carinii]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: oxidoreductase]] | [[Category: oxidoreductase]] | ||
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