3dbs: Difference between revisions

Line 20:

==About this Structure==

3DBS is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBS OCA].

3DBS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBS OCA].

==Reference==

The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin -4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer ., Folkes AJ, Ahmadi K, Alderton WK, Alix S, Baker SJ, Box G, Chuckowree IS, Clarke PA, Depledge P, Eccles SA, Friedman LS, Hayes A, Hancox TC, Kugendradas A, Lensun L, Moore P, Olivero AG, Pang J, Patel S, Pergl-Wilson GH, Raynaud FI, Robson A, Saghir N, Salphati L, Sohal S, Ultsch MH, Valenti M, Wallweber HJ, Wan NC, Wiesmann C, Workman P, Zhyvoloup A, Zvelebil MJ, Shuttleworth SJ, J Med Chem. 2008 Sep 25;51(18):5522-32. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/18754654 18754654]~~

[[Category: Homo sapiens]]

[[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]

~~[[Category: Single protein]]~~

[[Category: Ultsch, M.]]

[[Category: Wiesmann, C.]]

Line 34:

Line 33:

[[Category: Transferase]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Oct 8 09~~:05:~~10 2008~~''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:12:38 2009''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 20: / Line 20: @@
 ==About this Structure==
-DBS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBS OCA].
+DBS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DBS OCA].
 ==Reference==
-The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin -4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer ., Folkes AJ, Ahmadi K, Alderton WK, Alix S, Baker SJ, Box G, Chuckowree IS, Clarke PA, Depledge P, Eccles SA, Friedman LS, Hayes A, Hancox TC, Kugendradas A, Lensun L, Moore P, Olivero AG, Pang J, Patel S, Pergl-Wilson GH, Raynaud FI, Robson A, Saghir N, Salphati L, Sohal S, Ultsch MH, Valenti M, Wallweber HJ, Wan NC, Wiesmann C, Workman P, Zhyvoloup A, Zvelebil MJ, Shuttleworth SJ, J Med Chem. 2008 Sep 25;51(18):5522-32. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18754654 18754654]
+<ref group="xtra">PMID:18754654</ref><references group="xtra"/>
 [[Category: Homo sapiens]]
 [[Category: Phosphatidylinositol-4,5-bisphosphate 3-kinase]]
-[[Category: Single protein]]
 [[Category: Ultsch, M.]]
 [[Category: Wiesmann, C.]]
@@ Line 34: / Line 33: @@
 [[Category: Transferase]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  8 09:05:10 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 04:12:38 2009''