3e63: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3e63.jpg|left|200px]]


The entry 3e63 is ON HOLD until Paper Publication
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{{STRUCTURE_3e63|  PDB=3e63  |  SCENE=  }}


Authors: Antonysamy, S.S.
===Fragment based discovery of JAK-2 inhibitors===


Description: Fragment based discovery of JAK-2 inhibitors


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 8 09:18:25 2008''
==Disease==
Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myelofibrosis, idiopathic OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Myeloproliferative disorder with erythrocytosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Polycythemia vera OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Thrombocythemia, essential OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]], Budd-Chiari syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=147796 147796]]
 
==About this Structure==
3E63 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E63 OCA].
[[Category: Homo sapiens]]
[[Category: Non-specific protein-tyrosine kinase]]
[[Category: Single protein]]
[[Category: Antonysamy, S S.]]
[[Category: Atp-binding]]
[[Category: Chromosomal rearrangement]]
[[Category: Disease mutation]]
[[Category: Drug discovery]]
[[Category: Fragment based]]
[[Category: Jak2]]
[[Category: Kinase]]
[[Category: Membrane]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Polymorphism]]
[[Category: Proto-oncogene]]
[[Category: Sh2 domain]]
[[Category: Transferase]]
[[Category: Tyrosine-protein kinase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 15 15:27:43 2008''

Revision as of 13:27, 15 October 2008

File:3e63.jpg

Template:STRUCTURE 3e63

Fragment based discovery of JAK-2 inhibitors

Disease

Known disease associated with this structure: Leukemia, acute myelogenous OMIM:[147796], Myelofibrosis, idiopathic OMIM:[147796], Myeloproliferative disorder with erythrocytosis OMIM:[147796], Polycythemia vera OMIM:[147796], Thrombocythemia, essential OMIM:[147796], Budd-Chiari syndrome OMIM:[147796]

About this Structure

3E63 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Page seeded by OCA on Wed Oct 15 15:27:43 2008

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