3efj: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
3EFJ is a | 3EFJ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EFJ OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:18763753</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Receptor protein-tyrosine kinase]] | [[Category: Receptor protein-tyrosine kinase]] | ||
[[Category: Angelo, N D.]] | [[Category: Angelo, N D.]] | ||
[[Category: Bellon, S.]] | [[Category: Bellon, S.]] | ||
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[[Category: Tyrosine-protein kinase]] | [[Category: Tyrosine-protein kinase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 01:52:06 2009'' | ||
Revision as of 23:52, 16 February 2009
Structure of c-Met with pyrimidone inhibitor 7
Template:ABSTRACT PUBMED 18763753
Disease
Known disease associated with this structure: Hepatocellular carcinoma, childhood type OMIM:[164860], Renal cell carcinoma, papillary, familial and sporadic OMIM:[164860], Autism, suseptibility to, 9 OMIM:[164860]
About this Structure
3EFJ is a 2 chains structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- D'Angelo ND, Bellon SF, Booker SK, Cheng Y, Coxon A, Dominguez C, Fellows I, Hoffman D, Hungate R, Kaplan-Lefko P, Lee MR, Li C, Liu L, Rainbeau E, Reider PJ, Rex K, Siegmund A, Sun Y, Tasker AS, Xi N, Xu S, Yang Y, Zhang Y, Burgess TL, Dussault I, Kim TS. Design, synthesis, and biological evaluation of potent c-Met inhibitors. J Med Chem. 2008 Sep 25;51(18):5766-79. PMID:18763753 doi:10.1021/jm8006189
Page seeded by OCA on Tue Feb 17 01:52:06 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Receptor protein-tyrosine kinase
- Angelo, N D.
- Bellon, S.
- Whittington, D.
- Alternative splicing
- Atp-binding
- C-met
- Chromosomal rearrangement
- Disease mutation
- Glycoprotein
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Polymorphism
- Proto-oncogene
- Receptor
- Transferase
- Transmembrane
- Tyrosine-protein kinase
