1t3p: Difference between revisions
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New page: left|200px<br /><applet load="1t3p" size="450" color="white" frame="true" align="right" spinBox="true" caption="1t3p, resolution 1.60Å" /> '''Half-sandwich arene ... |
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[[Image:1t3p.gif|left|200px]]<br /><applet load="1t3p" size=" | [[Image:1t3p.gif|left|200px]]<br /><applet load="1t3p" size="350" color="white" frame="true" align="right" spinBox="true" | ||
caption="1t3p, resolution 1.60Å" /> | caption="1t3p, resolution 1.60Å" /> | ||
'''Half-sandwich arene ruthenium(II)-enzyme complex'''<br /> | '''Half-sandwich arene ruthenium(II)-enzyme complex'''<br /> | ||
==Overview== | ==Overview== | ||
The 1.6 [Angstrom] X-ray crystal structure of | The 1.6 [Angstrom] X-ray crystal structure of [(eta(6)-p-cymene)Ru(lysozyme)Cl(2)], the first of a half-sandwich complex of a protein, shows selective ruthenation of Nepsilon of the imidazole ring of His15. | ||
==About this Structure== | ==About this Structure== | ||
1T3P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with CL, NA, ACT and RU7 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http:// | 1T3P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] with <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=RU7:'>RU7</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T3P OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: Fishburne, K.]] | [[Category: Fishburne, K.]] | ||
[[Category: Habtemariam, A.]] | [[Category: Habtemariam, A.]] | ||
[[Category: Hunter, T | [[Category: Hunter, T M.]] | ||
[[Category: McNae, I | [[Category: McNae, I W.]] | ||
[[Category: Melchart, M.]] | [[Category: Melchart, M.]] | ||
[[Category: Sadler, P | [[Category: Sadler, P J.]] | ||
[[Category: Walkinshaw, M | [[Category: Walkinshaw, M D.]] | ||
[[Category: Wang, F.]] | [[Category: Wang, F.]] | ||
[[Category: ACT]] | [[Category: ACT]] | ||
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[[Category: tetragonal lysozyme]] | [[Category: tetragonal lysozyme]] | ||
''Page seeded by [http:// | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:09:32 2008'' | ||
Revision as of 13:09, 21 February 2008
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Half-sandwich arene ruthenium(II)-enzyme complex
Overview
The 1.6 [Angstrom] X-ray crystal structure of [(eta(6)-p-cymene)Ru(lysozyme)Cl(2)], the first of a half-sandwich complex of a protein, shows selective ruthenation of Nepsilon of the imidazole ring of His15.
About this Structure
1T3P is a Single protein structure of sequence from Gallus gallus with CL, NA, ACT and RU7 as ligands. Active as Lysozyme, with EC number 3.2.1.17 Full crystallographic information is available from OCA.
Reference
Half-sandwich arene ruthenium(II)-enzyme complex., McNae IW, Fishburne K, Habtemariam A, Hunter TM, Melchart M, Wang F, Walkinshaw MD, Sadler PJ, Chem Commun (Camb). 2004 Aug 21;(16):1786-7. Epub 2004 Jul 27. PMID:15306883
Page seeded by OCA on Thu Feb 21 15:09:32 2008
