3ela: Difference between revisions

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'''Unreleased structure'''
{{Seed}}
[[Image:3ela.jpg|left|200px]]


The entry 3ela is ON HOLD
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{{STRUCTURE_3ela|  PDB=3ela |  SCENE=  }}


Authors: Bjelke, J.R., Olsen, O.H., Fodje, M., Svensson, L.A., Bang, S., Bolt, G., Kragelund, B.B., Persson, E.
===Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor===


Description: Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 22 10:16:50 2008''
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{{ABSTRACT_PUBMED_18640965}}
 
==Disease==
Known disease associated with this structure: Factor VII deficiency OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]], Myocardial infarction, decreased susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227500 227500]]
 
==About this Structure==
3ELA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ELA OCA].
 
==Reference==
Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity., Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E, J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18640965 18640965]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Bjelke, J R.]]
[[Category: Fodje, M.]]
[[Category: Svensson, L A.]]
[[Category: Allosteric regulation]]
[[Category: Allostery]]
[[Category: Alternative splicing]]
[[Category: Blood clotting]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Disease mutation]]
[[Category: Egf-like domain]]
[[Category: Exosite]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Palmitate]]
[[Category: Pharmaceutical]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Transmembrane]]
[[Category: Zymogen]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  5 12:56:26 2008''

Revision as of 10:56, 5 November 2008

File:3ela.jpg

Template:STRUCTURE 3ela

Crystal structure of active site inhibited coagulation factor VIIA mutant in complex with soluble tissue factor

Template:ABSTRACT PUBMED 18640965

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this Structure

3ELA is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Mechanism of the Ca2+-induced enhancement of the intrinsic factor VIIa activity., Bjelke JR, Olsen OH, Fodje M, Svensson LA, Bang S, Bolt G, Kragelund BB, Persson E, J Biol Chem. 2008 Sep 19;283(38):25863-70. Epub 2008 Jul 17. PMID:18640965

Page seeded by OCA on Wed Nov 5 12:56:26 2008

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