User:Wayne Decatur/Suppression of RNA Silencing by Viruses: Difference between revisions
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RNA interference (RNAi) (also known as post-transcriptional gene silencing (PTGS) or RNA silencing) is an evolutionarily conserved cellular response to the presence of double-stranded (ds) RNA that functions as a gene inactivation system in many eukaryotes and relies on tiny RNAs as the targeting molecules. One function of RNA silencing is to act in surveillance against molecular parasites, such as viruses, several of which rely on double-stranded RNA for replication. Viruses have developed mechanisms to counteract RNAi by providing proteins that sequester siRNAs targeted against viral RNAs. | RNA interference (RNAi) (also known as post-transcriptional gene silencing (PTGS) or RNA silencing) is an evolutionarily conserved cellular response to the presence of double-stranded (ds) RNA that functions as a gene inactivation system in many eukaryotes and relies on tiny RNAs as the targeting molecules. One function of RNA silencing is to act in surveillance against molecular parasites, such as viruses, several of which rely on double-stranded RNA for replication. Viruses have developed mechanisms to counteract RNAi by providing proteins that sequester siRNAs targeted against viral RNAs. | ||
Several structures have provided insight into the basis for the molecular interactions responsible for | Several structures, listed below, have provided insight into the basis for the molecular interactions responsible for suppression of gene silencing (RNAi) by viruses. | ||
==Related Structures and Topics== | ==Related Structures and Topics== | ||
*[[User:Wayne Decatur/Tomato aspermy virus protein 2b Suppression of RNA Silencing]] | *[[User:Wayne Decatur/Tomato aspermy virus protein 2b Suppression of RNA Silencing]] | ||
