2zmm: Difference between revisions
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==Disease== | ==Disease== | ||
Known disease associated with this structure: | Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=176885 176885]] | ||
==About this Structure== | ==About this Structure== | ||
2ZMM is a | 2ZMM is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZMM OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:18798205</ref><references group="xtra"/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Wu, J.]] | [[Category: Wu, J.]] | ||
[[Category: Xu, W.]] | [[Category: Xu, W.]] | ||
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[[Category: Ptp1b]] | [[Category: Ptp1b]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:47:15 2009'' | ||
Revision as of 10:47, 17 February 2009
Crystal structure of PTP1B-inhibitor complex
Disease
Known disease associated with this structure: Insulin resistance, susceptibility to OMIM:[176885]
About this Structure
2ZMM is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Wan ZK, Lee J, Hotchandani R, Moretto A, Binnun E, Wilson DP, Kirincich SJ, Follows BC, Ipek M, Xu W, Joseph-McCarthy D, Zhang YL, Tam M, Erbe DV, Tobin JF, Li W, Tam SY, Mansour TS, Wu J. Structure-based optimization of protein tyrosine phosphatase-1 B inhibitors: capturing interactions with arginine 24. ChemMedChem. 2008 Oct;3(10):1525-9. PMID:18798205 doi:10.1002/cmdc.200800188
Page seeded by OCA on Tue Feb 17 12:47:15 2009
