2w26: Difference between revisions

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New page: '''Unreleased structure''' The entry 2w26 is ON HOLD Authors: Roehrig, S., Straub, A., Pohlmann, J., Lampe, T., Pernerstorfer, J., Schlemmer, K., Reinemer, P., Perzborn, E., Schaefer, M...
 
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'''Unreleased structure'''
{{Seed}}
[[Image:2w26.jpg|left|200px]]


The entry 2w26 is ON HOLD
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{{STRUCTURE_2w26|  PDB=2w26 |  SCENE=  }}


Authors: Roehrig, S., Straub, A., Pohlmann, J., Lampe, T., Pernerstorfer, J., Schlemmer, K., Reinemer, P., Perzborn, E., Schaefer, M.
===FACTOR XA IN COMPLEX WITH BAY59-7939===


Description: Fator Xa in complex with BAY59-7939


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{{ABSTRACT_PUBMED_16161994}}
 
==About this Structure==
2W26 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W26 OCA].
 
==Reference==
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor., Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E, J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16161994 16161994]
[[Category: Homo sapiens]]
[[Category: Lampe, T.]]
[[Category: Pernerstorfer, J.]]
[[Category: Perzborn, E.]]
[[Category: Pohlmann, J.]]
[[Category: Reinemer, P.]]
[[Category: Roehrig, S.]]
[[Category: Schaefer, M.]]
[[Category: Schlemmer, K.]]
[[Category: Straub, A.]]
[[Category: Blood coagulation]]
[[Category: Calcium]]
[[Category: Cleavage on pair of basic residue]]
[[Category: Egf-like domain]]
[[Category: Factor xa]]
[[Category: Gamma-carboxyglutamic acid]]
[[Category: Glycoprotein]]
[[Category: Hydrolase]]
[[Category: Hydroxylation]]
[[Category: Polymorphism]]
[[Category: Protease]]
[[Category: Secreted]]
[[Category: Serine protease]]
[[Category: Zymogen]]
 
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